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Biomedical subjects

M Barranquero

Publications and source records attributed to M Barranquero.

6 recordsLinked to original sources
PubMed1996

Neutrophil function in elderly persons assessed by flow cytometry.

It is well known that the immune response declines with senescence and it is suggested that these changes render an individual susceptible to infection, autoimmune phenomena and cancer. Bacterial and viral infections are a major cause of illness and death amongst aged subjects, and once infection is established, the elderly also have a diminished capacity to prevent its spread (1). The cellular and molecular basis for this age-related decline in immunocompetence are still unknown and, possibly, are related to an alteration in cell transduction mechanisms (2).

Aged↗
PubMed1995

CD8+ T cell subsets in aging.

Infections are major cause of illness and death amongst elderly people. Peripheral blood CD8+ T lymphocytes -which play a crucial role in host defence against viral infections-. are divided in subsets based upon the expression of several cell and activation markers. Since in senescence changes in peripheral blood CD8+ T lymphocyte compartment have been described, studies were performed to determine whether in aging there are variations in the peripheral blood CD8+CD38+, CD8+CD57+, CD8+HLA-DR+, CD8+CD45RA+ and CD8+CD45RO+ cell subset. A decrease in the CD8+CD45RA+ lymphocytes was observed, indicating that variations in the CD8+ compartment can take place with ageing.

ADP-ribosyl Cyclase↗
PubMed1989

[Nutrition and oral health in gerodontology].

Nutrition has got a great influence on oldness phenomena. That is why people of age need to keep a prudent and equilibrated nutrition, what is achieved by a regulated diet. A bad nutrition increases the risk in certain clinic situations and overfeeding can have terrific effects because it may desequilibrated the metabolism. The food of an ancient person requires a special attention: it must be soft and easily chewed. They do not tolerate abundant meals and radical changes on daily diet must be avoided. In the present work we analize the nutrition on an ancient person, its characteristics and nutritional requirements, as good as the nutritional effects on the edentale patient.

Aged↗
PubMedDate not supplied

T cell receptor V-segment frequencies in aged individuals.

The T V alpha and V beta cell specificities repertoire usage in aging subjects was studied by the use of seven different monoclonal antibodies specific for defined regions of the T cell receptor (TCR). Except for the V beta 8 subfamily, no differences were observed in the frequency of T cells bearing selected V alpha beta epitopes, between old and control subjects.

Adult↗