[The appearance of the obstructive ventilatory syndrome in patients with pulmonary tuberculosis according to the extent and duration of the disease (author's transl)].
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Biomedical subjects
Publications and source records attributed to M Basić-Grbac.
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The relationship between pathoanatomical changes in bronchial arteries and occurrence of chronic obstructive bronchitis (COB) and bronchial asthma (BA) was studied. Pathoanatomical changes in bronchial arteries were more frequently found in patients with COB and BA than in patients with other bronchopulmonary diseases, i.e. that bronchial circulation in patients with COB and BA is impaired. Due to these findings a theory of vasculary-metabolic explanation of pathogenesis of bronchial hyperresponsiveness is based on hypoperfusion and hypoxia of cellular structures in the bronchial wall. Hypoxia is supposed to be an endogenous change in the bronchial wall which causes bronchial hyperresponsiveness in various exogenous stimulants.
Case histories of 3 patients with primary mucociliary transport failure are described. Two of them had immotile cilia syndrome and one cystic fibrosis. In all three patients the same clinical picture was found and they had the same treatment, although the etiology of diseases was not the same. The treatment in two patients was not much successful since they had associated respiratory failure.
There is often a misguide of chronic bronchitis and passive pulmonary hypertension. In 42 patients with chronic bronchitis a revision of the results was made and it was found that in 28 (67%) patients the former diagnosis of chronic bronchitis was confirmed, while in 8 (19%) patients a new diagnosis was established--a passive pulmonary hypertension and in 6 (14%) patients a combination of chronic bronchitis and passive pulmonary hypertension was found. It is considered that the symptoms like cough, sputum and dyspnea as well as the similar physical finding may lead the clinician to change the diagnoses.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
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