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Biomedical subjects

M Basile

Publications and source records attributed to M Basile.

At least 55 records · Page 3Linked to original sources

Synthesis and pharmacological activity of some 1-alkylamino-3-(2'-methoxy-4'-diethylcarbamoyl-phenoxy)propan-2-ols.

The synthesis and pharmacological properties of some 1-alkylamino-3-(2'-methoxy-4'-diethylcarbamoylphenoxy)propan-2-ols, related to beta-adrenergic drugs, are described. The above compounds were found to possess beta 1 and beta 2-adrenolytic activity associated with local anesthetic and antiarrhythmic activities, which are clearly inferior to those of propranolol.

Adrenergic beta-Antagonists↗

[Agenesis of the femoral vein in the framework of vascular dysplasias of the lower limbs. Clinical case].

Venous dilatations of the lower limbs, especially if associated with others abnormalities, may reflect pathogenetic mechanisms far more complex and diverse than plain insufficiency of the sephena, all the way to congenital vascular anomalies of all possible types and still dubious classification. In such conditions a prerequisite of prime importance is the complete exploration of the whole arterial and venous vasculature of the limb, first of all in order to avoid rash therapeutic decisions, and then to help clarify the diagnosis and select the most appropriate treatment from among the numerous technics available.

Angiography↗

[Role of post-embolectomy anticoagulant therapy in the prevention of recurrences].

The authors review two homogenous groups of patients subjected to surgical embolectomy, one group receiving standard anticoagulant therapy before and after surgery, and the other not receiving that treatment regularly or at all. The results obtained in the two groups indicate that anticoagulant therapy plays a role of no mean order in the prevention of postoperative relapses.

Anticoagulants↗

[Role of the vasa vasorum in the process of remote vascularization of the Wesolowski Weavenit arterial prosthesis (experimental research)].

Experimental research was carried out for the purpose of studying the behaviour of the vasa-vasorum in a group of animals in which, by means of a Weavenit prosthesis, the section of aorta lying between the branches of the renal arteries and the trifurcation of the terminal oartic section had been substituted. From the results of the research the Authors conclude by asserting that above all the technique they used allowed excellent visualisation of the vasa-vasorum, as shown both by the histological preparation coloured with haematoxylin-eosin and by the preparations carried out under the stereomicroscope. Furthermore, in the microscopic observations there is the indisputable presence of vessels of varying calibre which, from the neo-adventitia through the meshes of the prosthesis, are carried to the level of the neointima, confirming that the vasa-vasorum constitute the most important reactive phenomenon for purposes of vascularisation of the prosthesis.

Animals↗