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Biomedical subjects

M Beckmann

Publications and source records attributed to M Beckmann.

35 records · Page 2Linked to original sources

[Osteogenesis imperfecta in pregnancy (author's transl)].

Osteogenesis imperfecta is one of the most frequent hereditary anomalies. One personal case is described. The literature is reviewed. The disease entity, the heredity and the possibilities of antenatal diagnosis are described. A pregnant patient with osteogenesis imperfecta needs careful antenatal care. Delivery by primary Caesarean section with gentle delivery of the infant is the method of choice. The aim of the method of delivery is to avoid spontaneous fractures during the delivery.

Adult↗

[Pregnancies following jejuno-ileal by-pass operation (author's transl)].

Two cases of pregnancy following by-pass operation from the Jejunum to the Ileum are reported. The by-pass operations were done for obesity. In 78 known pregnancies following by-pass operations many low birth weight infants were present. The weight pattern of the pregnant patients is uneven and not capable of giving clues to the birth weight of the infants. The risk for congenital malformations appears to be increased. The reason for this in unknown.

Adult↗

[Pregnancy and delivery combined with hereditory angioneurotic edema (author's transl)].

Two deliveries in a patient combined with hereditory angioneurotic edema are reported. Although even the smallest trauma can lead to life threatening edema the tendency to edema is reduced during pregnancy. Neither in the vagina nor the vulva the deliveries caused edema. The episiotomy did not cause a concomitant edema of the vulva, despite the predilection of the external genital organs for edema. It is possible that a correlation between the gonadotrophin level and the tendency to edema exists in hereditory angioneurotic edema.

Adult↗

[Unilateral hyperplasia of mammae during pregnancy].

The article reports on a case of marked unilateral hyperplasia of the mammae during pregnancy. Literature references show that this is a rare occurrence. The possible complications require an intensive control. Although malignant degeneration has not been reported, the authors believe that diagnostic clarification is mandatory.

Adenoma↗

[Biochemical and coagulation-physiology examinations before and after amniocentesis in early pregnancy].

In 46 women the alpha1-fetoprotein content, the soluble fibrin monomer complexes (LFMK), and the coagulation status were determined in the maternal serum at the beginning of the second trimester before and after amniocentesis. Increases of AFP by more than 100% of the original level pointed to fetomaternal microtransfusion, the quantity of which was calculated by means of a formula. Overall coagulation tests did not show any change after the puncture. A moderate LFMK increase was seen (p less than 0.05), which, however, was not clearly correlated with the AFP increase.

Amniocentesis↗

[Problems in the evaluation of contraceptives (author's transl)].

For the evaluation of the effectiveness of contraceptives the Life Table method is at present the best method. It is a disadvantage that the original method of Tietze & Potter was restricted to the evaluation of intra-uterine contraception devices. A Belgian team is now in the process of developing a modified life table method for the evaluation of the effectiveness and the side effects of oral contraceptives. The reference to the Pearl-index for the effectiveness of contraceptives is unclear and in the way in which it is at present used scientifically untenable.

Clinical Trials as Topic↗