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Biomedical subjects

M Bedö

Publications and source records attributed to M Bedö.

17 recordsLinked to original sources
PubMed1990

[Circulatory and respiratory parameters in children at cardiovascular risk].

Physical performance, pulse rate, blood pressure and respiratory functions (vital capacity, forced expiratory volume and maximal voluntary ventilation) in rest and during physical loading were studied in children of parents having had myocardial infarction under the age of 45. Children with normal and increased skinfold width, and with low resp. normal HDL-cholesterol levels were selected. The most unfavourable respiratory, circulatory and performance results were obtained in obese children with low HDL-cholesterol; significant differences were found in resting heart rate and maximal voluntary ventilation (MVV). In the author's mind, the primary factor is high body fat content resulting in poor physical activity and unfavourable HDL-cholesterol levels. All this forecasts a bad prognosis for adulthood in respect of cardiovascular disease.

Cardiovascular Diseases↗
PubMed1988

Longitudinal examinations in the course of dietotherapy of mentally retarded obese in-patients.

Mentally retarded obese in-patients were fed by low-energy diet (4.2-4.6 MJ) for 9 months. During this period, an average of 13 +/- 4.5 kg loss of body mass occurred in men and 16 +/- 2.7 kg in women. Anthropometric measurements were performed before starting the dietotherapy and in the ninth month. Changes of body fat could be followed well when calculated according to BMI. Less reliable results were obtained with skinfold thickness measurements, presumably due to body deformities. Results of clinical laboratory tests, which were carried out before starting the dietotherapy and in the fourth and seventh months, suggested that a low-energy-containing diet with balanced nutrient content and adequate protein intake did not impair protein metabolism, favourably affected serum triglyceride and cholesterol levels, but resulted in an unfavourable decrease in the HDL-cholesterol content.

Adult↗
PubMed1986

Risk factors in childhood diabetes mellitus.

The quotients total cholesterol/HDL-cholesterol and free fatty acid/albumin in serum were examined in various groups of diabetic patients and the changes of the quotients induced by various forms of physical activity were then registered. Both total cholesterol/HDL-cholesterol and free fatty acid/albumin were increased in patients with unsatisfactory control of diabetes. Low albumin levels were only seen in cases with very poor control or in cases afflicted by complications. Increased muscular activity unvariably led to a fall in the value of total cholesterol/HDL-cholesterol while in children with adequate control but performing little physical exercise the quotient of free fatty acid/albumin was low and total cholesterol/HDL-cholesterol was increased. In addition to the quotient of total cholesterol/HDL-cholesterol also the quotient of free fatty acid/albumin is a sensitive indicator of the diabetic condition.

Adolescent↗
PubMed1984

Effect of soya consumption on hepatic monooxygenase enzyme system and some lipid parameters in rats.

Young male rats were fed with diets containing Hungarian soya products (extruded or granulated soya preparates) as the only source of protein for four weeks. The weight gain of the animals, the cholesterol and triglyceride content of liver and the activity of the hepatic monooxygenase system were studied. 20% soya protein in the diet (either from extruded or from granulated soya products) supplemented with sulphur containing amino acids met the protein requirement of the young growing rats. In a separate experiment the protein depletion-repletion method was used to investigate the effect of Purina 500 E soya protein isolate on the above mentioned parameters. The results indicate that diets containing 20% soya protein are satisfactory for the regeneration of the protein depleted animals.

Animals↗
PubMed1983

Changes in cardiovascular risk factors in diabetic children during a camping holiday.

Diabetic children in a holiday camp were divided into two groups according to physical activity. In the active group a significant elevation of HDL-cholesterol and a highly significant decrease in total/HDL-cholesterol ratio were observed. In the inactive group similar but non-significant changes occurred. No appreciable changes were observed in the serum albumin level but the fasting FFA level decreased in both groups, more markedly in the active group. Therefore, the FFA/albumin quotient and also body fat percent decreased considerably in the active group while in the inactive group there were no significant changes.

Adolescent↗
PubMed1981

Survey of obesity in child communities.

Authors conducted the weight-height measurements of 12,751 children in the district of Monor on the basis of the IW/AH index and found 705 obese children. Childhood obesity rate of the district was 5.53%. The questionnaires sent to the affected children's families revealed diabetes in the families of 784 children, 66 of whom were obese, which is 8.4% - much higher than the populations's value. The highest obesity rate was found in puberty, while in children with a family background for diabetes this value was found in 14-18 years of age. The groups investigated are given special nursing. Authors express thanks to all the persons who contributed to carry out the measurements.

Adolescent↗
PubMed1978

Metabolic effects of clofibrate on experimental animals.

The effect of ethyl-alpha-(p-chlorophenoxy)-isobutyrate (clofibrate, Miscleron) on certain parameters of lipid and carbohydrate metabolism was studied in male and female white rats. The vitamin A content and the mixed function oxydase activity in the liver was also examined. 1. In short-term experiments over 10 to 30 days clofibrate significantly influenced the examined parameters. In a long-term experiment (9 months), however, these changes were no more observable. 2. Clofibrate exerted a protective effect against lipid mobilization following physical exercise (swimming). 3. No significant differences between male and female rats after clofibrate treatment could be observed.

Animals↗