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Biomedical subjects

M Behr

Publications and source records attributed to M Behr.

At least 19 recordsLinked to original sources

The influence of electron beam irradiation on the shear bond strength of glass-reinforced frameworks and veneer composites.

The bond between glass fibre framework and veneer composite can be achieved by silane coupling agents or by monomers that penetrate into a polymer network. However, it has been clinically demonstrated that his bond can fail. This study investigated whether electron beam irradiation improved the bond strength of fibre-frameworks and veneer composite with and without additional coupling agents.

Composite Resins↗

The influence of electron beam irradiation on fibre-reinforced composite specimens.

This study investigated whether glass fibre-reinforced composite (FRC) specimens can benefit from post-curing using electron beam irradiation. Twenty-four frameworks of the Vectris and 24 of the Stick glass fibre-reinforced system were veneered with their correspondent veneer materials. Eight specimens of both systems were post-cured using electron beam irradiation (3 x 33 kGy, 10 MeV). The specimens were fixed in a restrained-end apparatus and inserted in an artificial mouth. With the exception of controls (n = 8 each) all other groups were thermally cycled and mechanically loaded (TCML). Finally, all samples were loaded to fracture using a universal testing machine. In two of eight non-irradiated Vectris/Targis specimens facing fracture occurred during TCML. Irradiation avoided these failures. No Stick/Sinfony facing fractured. However, Stick frameworks showed considerable torsions. Post-curing with electron beam irradiation made Stick frameworks stiffer. The fracture load of irradiated Stick/Sinfony specimens reached 520 +/- 31 N; control (without TCML and irradiation) 396 +/- 14 N, TCML-group without irradiation 362 +/- 41 N. Irradiated Vectris/Targis had a fracture resistance of 575 +/- 57 N; the control 556 +/- 36 N and the TCML group without irradiation 383 +/- 51 N. This investigation demonstrated that different types of FRC systems could considerably benefit from electron beam irradiation. The reconstructions became stiffer and resisted higher load.

Composite Resins↗

Influence of stress simulation parameters on the fracture strength of all-ceramic fixed-partial dentures.

OBJECTIVES: This in vitro study tested the influence of diverse stress simulation parameters on the fracture strength of all-ceramic three-unit fixed partial dentures (FPDs). METHODS: All-ceramic FPDs made of Empress 2 (Ivoclar-Vivadent, FL) were exposed to thermal cycling and mechanical loading (TCML) with varying loading parameters such as chewing force (amount, frequency), thermal loading, lateral jaw motion, abutment material, artificial periodontium or antagonistic denture. To investigate the influence of the abutment material, human teeth, polymer abutments and alloy abutments were used. Two different TCML devices with pneumatic or weight loading were compared. FPDs without aging were used as a control. RESULTS AND SIGNIFICANCE: Combined thermal and mechanical loading significantly reduced the FPD fracture resistance from 1832N to 410N. Duplication of chewing frequency, phase load increase or additional lateral movement did not effect the results. Increasing chewing force, artificial periodontium, and antagonist or abutment material reduced the fracture resistance of the tested FPDs. Different devices with weight or pneumatic loading had no significant influence on the loading capacity of the FPDs. Artificial aging should be performed combining thermal cycling with mechanical loading. Simulation of the artificial periodontium, human antagonists and abutments should be included to achieve a significant aging.

Bite Force↗

Electron beam irradiation of denture base materials.

UNLABELLED: Electron beam irradiation can be used to influence the properties of polymers. It was the aim of this study to investigate whether PMMA denture base materials can benefit from irradiation in order to have increased fracture toughness, work of fracture or hardness. Rectangular specimens of heat-and auto-curing denture base materials were electron beam irradiated (post-cured) with 25, 100 and 200 kGy using an electron acceleration of 10 MeV or 4.5 MeV respectively. Fracture toughness, work of fracture, Vickers hardness and colour changes were measured and compared with not-irradiated specimens. The toughness, work of fracture and hardness increased using 10 MeV with a dose of 25 kGy and with 100 kGy using 4.5 MeV. However, the clinical use may not benefit from the observed small changes. Higher dosage (200 kGy) decreased the values significantly. The colour changes reached a level which was found to be not clinically acceptable. CONCLUSION: PMMA denture base materials do not benefit from post-curing with electron beam irradiation.

Dental Materials↗

Pedestrian lower limb injury criteria evaluation: a finite element approach.

OBJECTIVE: In pedestrian traumas, lower limb injuries occur under lateral shearing and bending at the knee joint level. One way to improve injury mechanisms description and consequently knee joint safety is to evaluate the ultimate shearing and bending levels at which ligaments start being injured. METHODS: As such data cannot easily and accurately be recorded clinically or during experiments, we show in this article how numerical simulation can be used to estimate such thresholds. This work was performed with the Lower Limb Model for Safety (LLMS) in pure lateral bending and shearing conditions, with an extended range of impact velocities. RESULTS: One result concerns the ultimate knee lateral bending angle and shearing displacement measurements for potential failure of ligaments (posterior cruciate, medial collateral, anterior cruciates and tibial collateral). They were evaluated to be close to 16 degrees and 15 mm, respectively. CONCLUSION: The lower leg model used in this study is an advanced FE model of the lower limb, validated under various situations. Its accurate anatomical description allows a wide range of applications. According to the validity domain of the model, it offered a valuable tool for the numerical evaluation of potential injuries and the definition of injury risk criterion for knee joint.

Accidents, Traffic↗

Composite veneering of metal based fixed partial dentures.

The aim of this in vitro study was to determine the thermal mechanical properties of veneering composites after polymerization with the appropriate polymerization device. Fracture tests were performed to investigate the effect on fixed partial dentures (FPDs). Dynamic mechanical thermal analysis was used to determine the temperature-dependent mechanical properties. To approximate the clinical situation, the fracture resistance of three-unit metal-based FPDs with different composite veneering was investigated after a simulated 5-year oral wearing period. The restorations were made of a high gold alloy and veneered with three different composites. To determine the influence of fabrication, one composite was used in a light-polymerizing and a heat/pressure-curing version and, in addition, a newly developed heat protection paste was used. After a 5-year simulation period, the fracture resistance was determined. The storage modulus varied between 14268 N mm(-2) (Belleglass) and 6616 N mm(-2) (Sinfony). Adoro showed no significant differences between light curing (9155 N mm(-2)) and heat curing (8184 N mm(-2)) variations. The Adoro-veneering with the heat protection paste showed the highest median fracture strength (1700 N), followed by Adoro LC (1555 N), Belleglass (1051 N), Adoro HP (1150 N) and Sinfony (909 N). The most common failure type occurring in all FPDs was a cracking of the composite, exposing the metal framework. All FPDs showed stress cracking of the composite. The heat protection paste seemed to reduce the crack formation after fabrication and increased the fracture resistance of the composite veneering. Stress cracking after thermal cycling and mechanical loading affected all composites, but all veneered three-unit alloy FPDs showed a fracture resistance sufficient for posterior application.

Composite Resins↗

Marginal adaptation in dentin of a self-adhesive universal resin cement compared with well-tried systems.

OBJECTIVES: This study compares the marginal adaptation of a new self-adhesive universal resin cement with only one application step, to the marginal adaptation of established cements and their corresponding adhesive systems. METHODS: All-ceramic crowns were inserted on human molars using a new self-adhesive universal resin cement without and with one pre-treatment step, a resin cement with a smear-layer removing and a compomer cement with a smear-layer dissolving adhesive system. After simulation of five years oral stress, the marginal adaptation was evaluated by dye penetration and scanning electronic microscope analysis using the replica technique. RESULTS: Scanning electron microscopy: all investigated luting agents showed comparable amounts of 'perfect margin' ranging between 88-98% (median). Dye penetration: the self-adhesive system had significantly lower dye penetration (18-25%, median). SIGNIFICANCE: The results indicate that a self-adhesive universal resin cement without pre-treatment can provide a marginal adaptation at dentin which is comparable to established luting agents.

Coloring Agents↗

In vitro fracture resistance and marginal adaptation of metallic and tooth-coloured post systems.

The aim of this in vitro study was to compare the fracture resistance and marginal adaptation of all-ceramic incisor crowns with all-ceramic posts, glass-fibre-reinforced posts and titanium posts as well as a control without any post. Three groups of eight maxillary incisors were restored with an all-ceramic post, a fibre-reinforced composite (FRC) post, a titanium post and a further group was restored without posts. Composite cores were provided and all-ceramic crowns were adhesively luted. After artificial ageing, the fracture resistance of the restored teeth was determined. The marginal adaptation of the restorations at the interfaces between cement-tooth and cement-crown was evaluated with scanning electron microscopy using replica specimen before and after ageing. The restored teeth without posts [270N (235/335)] showed no significantly different fracture strength compared with teeth with the titanium system [340N (310/445)]. The all-ceramic posts [580N (425/820)] and the FRC posts [505N (500/610)] both provided a significant higher fracture resistance than the teeth without posts. Prior to ageing, all materials showed <5% separation at the margins cement-tooth or cement-crown ('marginal gap'). After ageing, the interfaces of all systems deteriorated to values between 6 and 14% marginal gap. The greatest marginal gap was found with the titanium system (14%) at the interface cement-crown and with the all-ceramic posts (12%) at the transition between cement-tooth. Regarding fracture resistance and the marginal adaptation, the all-ceramic and FRC posts may be considered as an alternative to the commonly used titanium post restorations.

Cementation↗

Fracture resistance of fiber-reinforced vs. non-fiber-reinforced composite molar crowns.

UNLABELLED: This study compared fracture resistance of fiber-reinforced and non-fiber-reinforced composite molar crowns under simulated oral stress conditions. Three groups of fiber-reinforced composite crowns were constructed using one polyethylene fiber (belleGlass/Connect) and two glass fiber reinforcement systems (Sculpture/FiberKor, Targis/Vectris). The non-fiber-reinforced crowns based on the facing material alone: Sculpture, Targis or belleGlass. Additionally, crowns were made of the non-reinforced composite Artglass. Each group consisted of eight crowns. All crowns were luted to human molars and exposed to thermal cycling and mechanical loading (6000 x 5 degrees C/55 degrees C; 1.2 x 10(6x)50 N; 1.66 Hz). The fracture resistance was measured using a Zwick universal testing machine. RESULTS: The non-reinforced Artglass crowns demonstrated the highest fracture resistance, significantly higher than the resistance shown with belleGlass, belleGlass/Connect or Targis. Artglass showed an extremely wide distribution of values, however. No statistically significant differences were found between the reinforced and non-reinforced composite crowns of Vectris/Targis, FiberKor/Sculpture or Connect/belleGlass although the reinforced crowns showed a tendency towards higher values. The fracture resistance values scattered markedly more for the reinforced crowns, and their lowest fracture values also reached the level of the lowest non-reinforced crowns. The small distribution of fracture values for the non-reinforced crowns indicates that they will be less susceptible for manufacturing faults and more reliable under clinical conditions. CONCLUSIONS: RESULTS of this study suggest that single molar composite crowns (tested in this study) do not benefit from fiber-reinforcement.

Analysis of Variance↗

Marginal adaptation and fracture resistance of adhesively luted glass fibre-composite reinforced molar crowns with different inner crown surfaces.

OBJECTIVES: This study compared the influence of different inner crown surfaces on the fracture resistance and marginal adaptation of adhesively fixed glass fibre-reinforced molar crowns. MATERIALS AND METHODS: Vectris/Targis crowns were constructed with an inner framework of glass fibres (directly on the tooth) or an inner veneering composite layer between the fibre-framework and the tooth-substance. Both groups were sandblasted inside using Al(2)O(3); 50 microm grain size (200 kPa, 20 s) and silane coated. A control group had the inner fibre framework, but was neither sandblasted nor silane coated. The crowns were adhesively cemented on extracted human teeth, and thermally cycled and mechanically loaded (TCML: 6000 x 5 degrees C/55 degrees C; 1.2 x 10(6) x 50 N, 1.66 Hz). The marginal adaptation before and after TCML was evaluated and the fracture resistance was investigated using a Zwick universal testing machine. RESULTS: After TCML the proportion of 'perfect margin' of the control group decreased significantly at the interface crown/cement. For the variations with an inner fibre framework or inner composite layer the marginal adaptation or fracture resistance did not decrease significantly after ageing. The fracture resistance values were control: 1509N+/-486; inner fibre framework: 1896N+/-342; inner composite layer: 1754N+/-340. CONCLUSIONS: In the case of the investigated fibre framework and veneering composite, the inner surface of glass fibre-reinforced molar crowns can be covered with a composite layer or with a glass fibre framework. Both methods achieve comparable high fracture strengths and reliable marginal adaptation.

Aluminum Oxide↗

Helicobacter DNA in bile: correlation with hepato-biliary diseases.

BACKGROUND: Helicobacter has been identified in isolated cases of hepato-biliary diseases, but its role in the pathogenesis of these conditions remains unclear. AIM: To determine whether Helicobacter could be detected in bile obtained at endoscopic retrograde cholangiopancreatography, and to evaluate the prevalence of this infection in patients with hepato-biliary diseases. METHODS: Bile was collected from 125 patients with various hepato-biliary diseases undergoing endoscopic retrograde cholangiopancreatography. Among them, 75 were diagnosed with biliary stones, 15 with pancreatico-biliary malignancies and four with primary sclerosing cholangitis. The detection of Helicobacter in DNA extracted from these bile samples was performed using Helicobacter genus-specific primers (capable of detecting 100-1000 organisms/mL). RESULTS: Helicobacter was detected in all positive controls. Only three samples had polymerase chain reaction inhibitors. All remaining bile samples (122 patients with hepato-biliary diseases) were negative for Helicobacter DNA. CONCLUSIONS: Helicobacter can be detected in bile samples using polymerase chain reaction. This infection, however, was not present in any of our patients diagnosed with gallstones or hepato-biliary malignancies, raising doubt as to the possible association between Helicobacter and these entities. Given the low sample size of patients with primary sclerosing cholangitis, more studies are required to determine whether an association exists with this condition.

Adolescent↗

Fixed partial dentures: all-ceramics, fibre-reinforced composites and experimental systems.

The aim of this in vitro study was to compare the fracture strength of three-unit FPDs (fixed partial dentures) and three-unit inlay FPDs after a simulated 5-year oral wearing period. The restorations were made of a pressable all-ceramic (Empress 2) and two specially designed, experimentally fixed partial dentures combining ceramics with dental composite. Three-unit FPDs and inlay FPDs were manufactured and were adhesively luted onto human molars. After thermal cycling and mechanical loading in an artificial environment, the fracture strength was determined. Zircon-based milled ceramic (Lava) three-unit FPDs were used as a control. The zircon ceramic and the fibre-based ceramic three-unit FPDs showed median fracture values between 1000 and 1400 N. For composite veneered zircon FPDs a fracture strength of about 800 N and for all-ceramic Empress 2 of about 350 N could be determined. The results for the inlay FPDs were between 1300 N and 1400 N for FRC/ceramic, 1000 N for zircon/composite and 500 N for all-ceramic restorations. The all-ceramic showed higher fracture resistance applied as inlay FPDs. The described hybrid techniques combining ceramics and composites could represent an interesting procedure for further investigations and, eventually, clinical implication.

Aluminum Silicates↗

A human model for road safety: from geometrical acquisition to model validation with radioss.

In order to investigate injury mechanisms, and to provide directions for road safety system improvements, the HUMOS project has lead to the development of a 3D finite element model of the human body in driving position. The model geometry was obtained from a 50th percentile adult male. It includes the description of all compact and trabecular bones, ligaments, tendons, skin, muscles and internal organs. Material properties were based on literature data and specific experiments performed for the project. The validation of the HUMOS model was first achieved on isolated segments and then on the whole model in both frontal and lateral impact situations. HUMOS responses were in good agreement with the experimental data used in the model validation and offers now a wide range of applications from crash simulation, optimization of safety systems, to biomedical and ergonomics.

Abdomen↗

The seated man: geometry acquisition and three-dimensional reconstruction.

A three-dimensional (3D) virtual human body in seated position can be used in a wide range of applications such as basic or clinical research. A male cadaver placed in the driving position in a car cockpit was frozen. Strictly parallel 5 mm thickness serial sections were then performed. Both sides of the slices were photographed, scanned and analyzed by anatomists with software tools, in order to produce accurate contours of the identified anatomical structures. A 3D reconstruction of organs, based on the marching cubes method, was achieved except for thin structures. This allowed an anatomical validation of these reconstructed elements. The result of this work is a complete geometrical database of a seated human body in the driving position including skin, all bones, internal organs and main muscle groups.

Aged↗

Frequency and costs of technical failures of clasp- and double crown-retained removable partial dentures.

OBJECTIVES: The aim of this study was to evaluate the frequency of technical failure rates and the maintenance costs of clasp- or double crown-retained removable partial dentures (RPDs) (parallel-sided and conical double crowns). MATERIAL AND METHODS: According to three different retainer systems used between January 1992 to December 1998, three subgroups were randomly assigned from a group of 181 patients consisting of forty cases each. The average observation time was 4.2+/-1.7 years, with a minimum of 1.0 years and a maximum of 6.9 years. Technical complications such as fractures of the artificial teeth, loss of cementation, loss of facings as well as fractures of the metal framework and the soldering were recorded due to the medical reports. RESULTS: Twenty percent of all clasp-retained dentures showed technical complications during the observation period, whereas 50% of conical crown-retained (CC) and 32.5% of the parallel-sided retained dentures (PS) required repair. Most often reported was loss of cementation for double crowns (n=13, 32.5% PS; n=8, 20% CC) and fractures of the clasps (n=5). Although clasp-retained dentures had a markedly lower frequency of failures (n=8) than double crown systems (n=31), the calculated repair costs per event during the observation time were more than twice as high for clasp-retained dentures (172.5 Euro) than for double crown systems (8-78 Euro). The hypothesis that the maintenance costs of the more sophisticated double crown system are higher must be rejected.

Acrylic Resins↗

In vitro study of fracture strength and marginal adaptation of polyethylene-fibre-reinforced-composite versus glass-fibre-reinforced-composite fixed partial dentures.

This in vitro study was carried out in order to estimate the clinical usability of adhesively luted three-unit posterior fixed partial dentures (FPD) made of a polyethylene-fibre-reinforced-composite system (PFRC) in comparison with a glass-fibre-reinforced-composite system (GFRC). Therefore the fracture strength and marginal adaptation were examined. A total of 16 FPDs of each material combination were manufactured and adhesively luted to human molars. Before and after an artificial ageing process by thermal cycling and mechanical loading (TCML) the quality of the marginal adaptation was examined by evaluating epoxy replicas in a scanning electron microscope (SEM). After TCML the fracture strength of eight FPDs of each series was tested by mechanical loading them to failure. With the remaining eight FPDs the quality of deeper layers of the luting was examined with a dye penetration technique. The calculated median fracture strength values (25/75% percentiles) were 830 N (643/982) for the PFRC and 884 N (684/1,113) for the GFRC. The SEM analysis showed at least 80% of perfect marginal areas for both material combinations in dentine as well as in enamel before and after TCML. Looking at the cement-tooth interfaces the dye penetration technique showed statistically significant better results for the enamel finishing lines than for those in dentine. With finishing lines in dentine the two material combinations showed statistically significant differences for this interface. Fracture force results as well as marginal quality encourage further clinical investigations on both systems although the GFRC performed slightly better than the PFRC.

Cementation↗

Comparison of three types of fiber-reinforced composite molar crowns on their fracture resistance and marginal adaptation.

UNLABELLED: Three types of fiber-reinforced composite (FRC) molar crowns were tested on their fracture resistance and marginal adaptation under simulated oral stress conditions. Two glass fiber systems, one processed with a vacuum/pressure system, the other by manual fiber adaptation, and a polyethylene fiber system were evaluated. Every group consisted of 12 crowns. All crowns were luted adhesively on human molars and exposed to thermal cycling and mechanical loading (TCML: 6000 x 5 degrees C/55 degrees C; 1.2 x 10(6) x 50N; 1.66Hz). The marginal adaptation was evaluated through dye-penetration and analyzed semi-quantitatively with a scanning electron microscope. The fracture resistance was measured using a Zwick universal testing machine. The highest fracture resistance was observed on the glass-fiber systems (FibreKor/Sculpture 1875N +/- 596; Vectris/Targis 1726+/-542), though statistically, the polyethylene system (belleGlass/Connect 1388+/-620) was not significantly weaker. All systems exceeded the fracture resistance required to withstand the maximum masticatory forces expected in the molar region. The marginal adaptation generally had a tendency towards larger gaps after TCML. The crown/composite-cement bond deteriorated significantly after TCML with the manual fiber adaptation and the polyethylene fiber system. The cement/tooth bond strength depended on which composite-cement/dentin-adhesive system was used. CONCLUSION: The fracture resistance of molar crowns made of glass-fiber reinforced composite was higher than those of polyethylene fiber-reinforced composite crowns. However, there was no statistically significant difference. The marginal adaptation seems to depend on the fiber systems and composite-cement/dentin adhesive system used.

Analysis of Variance↗