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Biomedical subjects

M Berghuis

Publications and source records attributed to M Berghuis.

6 recordsLinked to original sources
PubMed1991

[Continuous arteriovenous hemofiltration and hemodiafiltration in a newborn infant with acute kidney insufficiency].

A boy of 10 days old with acute renal failure was treated with continuous arterio-venous hemofiltration and continuous arterio-venous hemodiafiltration over a period of 14 days. Hemodynamically both technics were well tolerated. Fluid overload was treated effectively by continuous fluid withdrawal and during continuous arterio-venous hemodiafiltration there was an adequate solute removal. One bleeding episode was observed during controlled general heparinization and was probably related to thrombopenia. In conclusion, continuous arterio-venous hemofiltration and hemodiafiltration are efficient modes of treatment in hemodynamically unstable infants in whom other forms of conventional dialytic therapy are contraindicated. Only continuous arterio-venous hemodiafiltration offers both fluid withdrawal and adequate solute removal and consequently may be preferred to continuous arterio-venous hemofiltration.

Acute Kidney Injury↗
PubMed1988

Surface hydrophobicity and opsonic requirements of coagulase-negative staphylococci in suspension and adhering to a polymer substratum.

The opsonic requirements for phagocytosis in suspension of 38 clinical isolates of coagulase-negative staphylococci recovered from neonates with septicemia were found to be related to the degree of surface hydrophobicity of these strains. Sixteen isolates were adequately opsonized only in the presence of complement; this group was significant more hydrophobic (p less than 0.001) than the 22 strains not requiring complement for efficient uptake in suspension. Evidence showed that hydrophobic groups present on the bacterial surface may interfere with IgG opsonization. In contrast, IgG sufficed as an opsonin without complement being required for the efficient uptake of these hydrophobic strains when adhering to a polymer surface.

Bacterial Adhesion↗
PubMed1987

[Reye's syndrome].

Reye's syndrome, characterized by acute encephalopathy and fatty degeneration of the viscera with hepatic failure, is a life-threatening illness that affects children of all ages. Although Reye's syndrome has been investigated extensively, its etiology and pathogenesis remain obscure. Metabolic pathophysiology appears to include a process affecting liver mitochondria. Recently disturbances in fatty acid oxidation have been described with a similar clinical picture. The cause of these events is presumably related to triggering viral illnesses, in ways that are unclear. Since prompt treatment might provide a better chance for recovery, early diagnosis is important.

Brain Diseases↗
PubMed1983

[A patient with neonatal citrullinemia].

In a four days old neonate, showing feeding difficulties, temperature imbalance, convulsions and coma, citrullinaemia was diagnosed. Subsequent treatment, consisting of protein-restriction, exchange transfusions, arginine suppletion and using an alternative pathway for waste nitrogen excretion (through sodium benzoate administration), resulted in a stable clinical and biochemical condition. Aged ten months, our patient shows a normal growth with psychomotor retardation probably linked with the perinatal events. Because it seems possible nowadays to prolong survival in neonates with inborn errors of urea synthesis, prompt and correct diagnosing of these disease entities becomes urgent in view of the long-term prognosis for the children involved.

Amino Acid Metabolism, Inborn Errors↗