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Biomedical subjects

M Bergoin

Publications and source records attributed to M Bergoin.

At least 55 records · Page 3Linked to original sources
PubMed1986

Excision of hemivertebrae in children with congenital scoliosis.

This study reports the authors' experience with excision of hemivertebrae in the treatment of congenital scoliosis. Although it is limited to 10 cases, it is significant because of the 9 years follow-up. The first patients treated have already passed the age of puberty and this is the most interesting aspect of the study.

Age Factors↗
PubMed1984

[Disk calcifications in children. Apropos of 17 cases].

Seventeen cases of calcification of the intervertebral discs in childhood have been seen. Only cervical lesions gave symptoms. In several cases the lesions were multifocal (cervical and thoracic) and there was a familial history in one case. Two cases were observed for 10 and 8 years respectively. It was noted that cervical calcifications tend to disappear while thoracic ones persist but are asymptomatic. The authors postulate that this is due to differences in the physiology of the nucleus and in the biomechanics at different levels of the spine. A high frequency of associated spinal deformities was noted. For this reason, the late prognosis must be guarded.

Calcinosis↗
PubMed1981

[Resection of hemivertebrae. A review of seven cases (author's transl)].

The technique used by the authors for removal of hemivertebrae is fully described. Two approaches are made, one posterior and one lateral at the same surgical session. This allows satisfactory control of roots, medulla and radicular vessels. The indications are described with reference to the age of the patient, the level of the lesion and the type of anomaly. It is concluded that it is a valuable procedure in progressive severe congenital scoliosis. 7 cases are reported without any neurological complication.

Adult↗
PubMed1977

[Dissolution of polyhedra of the nuclear polyhedrosis virus of the leatherjacket Tipula paludosa MEIG. Ultrastructural study of the virion (author's transl)].

The inclusion bodies of the nuclear polyhedrosis virus of T. paludosa MEIG. were purified by sucrose density gradients, their morphology described using scanning electron microscopy, and the conditions for their solubilization investigated. These inclusions known to be unusually resistant to dissolution, were successfully dissolved in conditions maintaining the integrety of the virus particles by using a 0.125 M sodium thioglycolate + 0.125 M sodium bicarbonate solution, pH 10.5. The virions extracted from the inclusions were purified by sucrose density gradients and their fine structure studied in electron microscopy. In PTA-stained preparations the virion is rod-shaped measuring 230--240 nm in length and 100 to 110 nm in diameter. It consists of an inner nucleocapsid surrounded by a loose envelope. Partially degraded virions reveal small subunits arranged in a regular helix (pitch of approximately 40 A) at the surface fo the capsid. These subunits likely represent the virus capsomers. A flexuous ropelike structure protruding at one end of the capsid is sometimes observed in partially degraded virions stained with uranyl acetate. In thin sections of infected hemocytes, the virions occluded on polyhedra or free in the nucleoplasm exhibit the same morphology although their diameter does not exceed 80--85 nm. The muclear polyhedrosis virus of T. paludosa meets all the criteria for incorporation into the Family Baculoviridae.

Animals↗
PubMed1977

Characterization of the Drosophila C virus.

Some properties of Drosophila C virus (DCV), a non-occluded isometric virus, have been studied. The virus particles were 30 nm in diam., their sedimentation coefficient was 153S and their buoyant density was 1-34 g/ml in caesium chloride in the pH range 7 to 9. These particles contained about 31% ribonucleic acid (RNA) and 69% protein. The reaction of formaldehyde with DCV particles suggested that the RNA in situ is single-stranded. The infectivity of DCV was stable at pH 3. The virus capsid contained three major polypeptides with mol. wt. of 31000, 30000 and 28000, and two minor components of mol. wt. 37000 and 8500. Virus preparations also contained a small number of infective particles 24 nm in diam. banding at a density of 1-44 g/ml. Preliminary results indicated that these heavy particles probably correspond to the dense particles recently reported in several vertebrate picornaviruses. RNA extracted from DCV was single-stranded and infectious. Its mol. wt. was calculated to be approx 3 X 10(6). It is proposed that this virus be included in the enterovirus group. The crytogram of the virus is R/1:3.0/31:S/S:I/O.

Animals↗