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Biomedical subjects

M Bettex

Publications and source records attributed to M Bettex.

At least 37 records · Page 2Linked to original sources

Extrinsic enteroureteroplasty: a piggyback technique for mid-ureteric replacement.

Replacement of the ureter was performed in 10 piglets using a serosa-lined intestinal tube. It was constructed by plication of the intestine and closing it at the antemesenteric border. The tube was then interposed to bridge a ureteral defect of variable length (4-6 cm). Information from IVU and macroscopic and microscopic results showed that the function of the interposed segments was achieved in all cases, however, with significant stenosis in the absence of adequate postoperative splinting in 5 cases, and neomucosa - similar to uroepithelium in the beginning and a complete urothelium after 3 months - covered the interpositioned tube.

Animals↗

[Double kidney with ureterocele].

Twenty-six children with ureteroceles--twenty-three with unilateral double collecting system and three with bilateral double kidney--are analyzed. The clinical and radiological features of these ureteroceles are presented. The different possibilities of surgical management and their results are discussed. In 14 of these children we performed resection of the ureterocele with en bloc reimplantation of both ureters. Eleven cases were treated by resection of the ureterocele and upper pole nephroureterectomy and four cases by nephroureterectomy. Vesicoureteral reflux in both renal pelvic moieties was found in five cases after ureteral reimplantation en bloc. Because of frequent bilateral disease (10%) and the common association of other urological malformation it is preferable to try to perform ureteric reimplantation rather than primary nephroureterectomy even when the possibility of postoperative reflux is considered.

Child, Preschool↗

Endocrinologic aspects and problems in neuroblastoma. Pediatric surgical considerations.

In addition to chemotherapy and radiotherapy, surgery still has a place in the treatment of neuroblastoma, even though this place is no longer a central one. As has been obvious for some time, the treatment of malignancies is no longer the task of one physician. The teamwork of the chemotherapist, radiotherapist and surgeon has produced unforeseen successes, far superior to those obtained by any single modality. The immunologists are also at work in the laboratory; we surmise that they will provide us with additional surprises sooner or later.

Animals↗

[Surgical indications in cardial insufficiency in infants].

Indications for fundoplication in 70 infants with cardiac sphincter insufficiency are analysed and subdivided into absolute and relative indications in accordance with complications conditioned by reflux. Endoscopy has proved to be the most important diagnostic method for deciding whether antireflux surgery is necessary. It enables proof or exclusion of oesophagitis as the most frequent and most severe consequence of reflux. Functional tests, such as manometry and long-term measurement of pH, are important especially in cases where severity and pattern of the disease have not been clarified. Such tests enable assessment of the function of the cardia and tubular oesophagus, and hence the hazards to which the oesophagus is exposed by the reflux of the gastrointestinal contents. Hence, they represent a contribution to a reduction of the incidence rate of surgery to the absolute minimum which is a "must" at this age, without exposing the young patient to the risk of a serious complication.

Cardia↗

[Ultrasonographic antenatal detection of obstructed bladder (author's transl)].

The antenatal diagnosis of bladder obstruction may be possible by ultrasonography of the mother. We report herein four cases of prenatally detected megacystis: two were Prune Belly syndromes, one of which was aborted. The two others were female infants, one had a megacystis-microcolon-hypoperistalsis syndrome, in the other hypoperistalsis was present along with megacystis. Transuterine-transfetal bladder taps were used to relieve bladder pressure in utero.

Child, Preschool↗

[Paediatric urethral injures: initial management and long-term results (author's transl)].

Thirteen cases of urethral trauma in childhood are reported. The nature and management of such injuries are discussed. As a rule urethral ruptures are difficult to treat but long term results are surprisingly good irrespective of the initial procedure. Nevertheless, we do have the impression that with an initially aggressive operative treatment - aimed at a good anatomic reconstruction of the urethra - this goal is achieved much faster and with less complications.

Child↗

[The lower esophageal sphincter in newborn infants. Manometric study].

Lower esophageal sphincter manometry was conducted in 30 normal neonates aged from 4 hours to 9 days, using a technique known as continuous withdrawal with a constant perfusion rate in the catheter. A zone of raised pressure exists at the cardia level from birth, mean pressure recorded being 24.2 +/- 6.2 mmHg, and mean length of the high pressure zone being 11.1 mm. The sphincter acts in a manner that is comparable in all respects with that observed in older subjects, and the hypothetical "postpartum maturation" of the sphincter is an unlikely event. Manometric techniques need to be adapted to the particularly delicate situation encountered in neonates, the risk of error being high because of the reduced length of the sphincteric zone.

Cardia↗

Factor analysis of craniofacial morphology in complete bilateral cleft lip and palate.

The lateral roentgencephalograms of 29 children with repaired complete bilateral clefts of the lip and palate (BCLP) were compared with those of an equal number of non-cleft children matched for age (+/- 0.9 yr.) and sex. Of 21 spatial, angular, and linear measurements used to evaluate craniofacial skeletal morphology, 11 showed significant differences between the groups. Using factor analysis, covariation between variables was reduced to a set of six factors: I cranial base; II mandible; III palate; IV lower face; V nasomaxillary-pharyngeal complex; VI clivus. The six-factor solution accounts for 91.7 percent of the variance. Factors II, III, and V provide the best discrimination between BCLP and noncleft individuals.

Adolescent↗

Mortality after operation for hiatus hernia.

When we started this investigation we were convinced that we would not be able to collect enough fatal cases to enable us to analyse the various causes of death following operation for hiatus hernia. To our surprise, inquiries made at 53 paediatric surgical centres produced a total of 67 fatalities. Most of these deaths could have been prevented if the following rules would have been followed: 1. The diagnosis must be made early and therapy must be commenced as soon as possible before there is a deterioration of the patient's general state of health increasing the risk of operation. 2. It is important to be familiar with the various operative techniques and the possible complications which they can produce. 3. Follow-up examinations are essential as certain complications will be detected by the patient himself only too late! Mortality and morbidity of hiatus hernia should be very small if the correct treatment has been carried out. Nissen's fundoplication, Rehbein's hiatal plasty and gastropexy, Lortat-Jacob/Grob's oesophagogastropexy and their modifications, all carry a low mortality and are followed by good results stopping the gastro-oesophageal reflux.

Child↗

[Reflux esophagitis: operative procedures in children: fundoplication (author's transl)].

Hiatus hernia and peptic esophagitis in children lead in 20% of the cases to peptic stenosis, thus rendering a reflux-preventing operation mandatory in many patients. We consider fundoplication as the operation of choice and have used it for 17 years. The early and late mortality varies between 1.2% and 1.4% and can be lowered even further through improvement of treatment. Functional complications such as "gas bloat syndrome," dysphagia, diarrhea, disappear spontaneously in the first 2-3 months after surgery. The only severe late complication is the development of a paraesophageal hernia months after surgery: This complication can be avoided through better technique. Out of 61 patients who were examined 10 or more years after operation, 58 are totally free of symptoms.

Age Factors↗

Fundoplication in hiatal hernia--results after 10 years.

Of the 194 fundoplications for hiatus hernia published by the authors at an earlier date, 66 were done before 1965 and 61 were available for an evaluation of the results after 10 years. Clinical results are good, 58 patients being free of symptoms. Only 3 complained of diarrhea or slight dysphagia. The radiological check up was ideal in 59 cases. 2 patients showed an "en bloc" herniation, but the fundoplication worked still very well as a reflux-preventive mechanism. 40 patients were no'longer able to vomit, a fact that has been suspected by other authors. Only 14 of them resented this as an inconvenience.

Child, Preschool↗