Harnessing computer technology for behavioral therapy training and research.
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Behavior Therapy↗
Biomedical subjects
M Billings
Publications and source records attributed to M Billings.
Long-term follow-up of duodenal ulcer patients.
The CURE peptic ulcer clinic started in April 1974. Patients (mostly veterans) with documented ulcer disease were interviewed regularly and inpatient hospitalizations were reviewed for follow-up periods of up to 6 years. Data from 245 male ulcer patients, 190 with duodenal ulcer alone and 55 with both documented duodenal ulcer (DU) and gastric ulcer (GU), were analyzed to assess the natural history of ulcer disease and factors predicting the severity of its course. Eleven percent of clinic patients had a complication (bleeding requiring a transfusion, perforation, or obstruction) during follow-up. Complication rates were about 2.7% per year for those with no prior complication, and about 5% per year for those with a prior complication. No patient variables or ulcer markers were related to the likelihood of a complication. Patients with both DU and GU were similar to patients with DU alone on many background variables, but the combined ulcer group had a significantly higher frequency of blood group nonsecretors, increased incidence of cigarette smoking, and greater frequency of complications or ulcer hospitalization prior to entry into the study and during follow-up. These factors, together with our failure to find differences in aggressive factors (acid output and PGI), suggests that DU + GU represents a different disease entity marked by additional defects in mucosal defense.(ABSTRACT TRUNCATED AT 250 WORDS)
Adult↗
Inexpensive double-antibody fluoroimmunoassay for aminoglycoside antibiotics, phenytoin, and theophylline in serum.
We describe simple, clinically useful double-antibody fluoroimmunoassays for amikacin, gentamicin, tobramycin, theophylline, and phenytoin. The fluorescent tracers were prepared by conjugation to fluorescein isothiocyanate; the antisera were raised in rabbits. A simple filter fluorometer and disposable culture tubes are used. The tracer, sample, and first and second antibodies are combined and incubated at room temperature for 30 min. A precipitation-acceleration buffer is added, the samples are centrifuged, and the fluorescence of the supernate is measured directly in the assay tube without decantation. Interferences, usually negligible, can be corrected for by use of a sample blank. Results compare favorably in performance with various commercially available RIA and enzyme immunoassays.
Aminoglycosides↗
Outsourcing: considerations for healthcare protection managers.
The author discusses the use of contract services--myths, advantages, and disadvantages. He provides tips on what to look out for and what questions to ask before making a change to contract security.
Cost Control↗