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Biomedical subjects

M Blasco

Publications and source records attributed to M Blasco.

26 records · Page 2Linked to original sources
PubMed1992

[Factors associated with hypoalphalipoproteinemia].

BACKGROUND: Hypoalphalipoproteinemia (HALP) is the most frequent lipid alteration found in patients with myocardial infarction at an early age. It is defined by amounts of lipid cholesterol at high density lipoproteins (cHDL) lower than 10% according to age and sex. The aim of this study was to know the frequency of main factors which reduce the levels of cHDL in a group of subjects with and without HALP. METHODS: Pathological antecedents, consumption of drugs, alcohol and cigarettes, the presence of obesity and levels of cholesterol, triglycerides, cHDL, glucose and urea were studied in a group of 1825 males. The study was performed in the course of medical examinations for workers. RESULTS: The consumption of cigarettes, the index of body mass (IBM) and the prevalence of diabetes mellitus were higher in the group of subjects with HALP. Hypertriglyceridemia (triglycerides > or = 200 mg/dl) was found in 31% of the subjects with HALP vs 10% in the control group (p < 0.001); hypocholesterolemia (cholesterol < or = 150 mg/dl) was also significantly greater (9.8% vs 4.3%, p < 0.01). Altogether, in 64% of the subjects with HALP, factors which may decrease cHDL were associated. Of the factors studied, the number of triglycerides, IBM and the number of cigarettes consumed per day were the independent factors which most significantly contributed to the decrease of cHDL in the regression analysis. CONCLUSIONS: Most of the subjects with hypoalphalipoproteinemia present other modifiable factors such as an elevated index of body mass, cigarette consumption and high amounts of triglicerydes, the correction of which constitutes the base for treatment of this disorder.

Adult↗
PubMed1992

In vitro lithotripsy with the Alexandrite laser.

The Alexandrite laser system has proven to be an effective and safe method of ureteral lithotripsy. Some authors have recently reported the risk of interspersion of fiber splinters into tissue during lithotripsy, when short pulses and high power densities are employed. In vitro lithotripsy on renal calculi artificially placed in human ureters was realized under the parameters of a manufactured model (Alexantriptor, HMT). We have observed neither interspersion of fragments nor ureteral damage. These in vitro experiments and our clinical experience confirm that Alexandrite laser lithotripsy is reliable and safe.

Humans↗
PubMed1991

Lithotripsy with the alexandrite laser: our initial 100 clinical cases.

The alexandrite laser system has proven to be an effective and safe method of treating ureteral stones. When the electromagnetic energy of a laser light pulse is selectively absorbed by the stone, a plasma forms at the surface. This plasma, which is composed of ions and electrons, continues to absorb laser energy, reaching very high pressure and generating a shock wave that fragments the stone. The degree of stone fragmentation is directly related to the composition and crystal lattice structure of the calculus. 112 calculi have been treated, and laser lithotripsy was successful in 87.5%. 6% of the stones were inadvertently flushed back into the kidney. No patient required an open ureterolithotomy. Guidance of the laser fiber onto the stone was performed by rigid ureteroscopy. There were no troublesome complications, and in a 3-month follow-up, no sequelae were reported.

Adult↗
PubMedDate not supplied

[Control of respiratory monitoring in the critical patient].

This study of the safety of patients undergoing mechanical ventilation was undertaken to ensure correct ventilation and to find quality-control elements for patients and nursing staff. Differences in mode programming and ventilation parameters and their registry at the change of nursing shifts, and correct programming of the sensitivity and minimum minute volume alarms and maximum airway pressure alarms were examined. In a two-month period, 8 cross-sectional studies were made of G1 prevalence in each of three nursing shifts. The status of the alarms and sensitivity were recorded when incorrect, as well as whether the ventilation mode and parameters coincided with the change of nursing shift. An analysis was made of: FiO2, PEEP, respiratory rate, minute volume, tidal volume, support pressure level, and control pressure level depending on the ventilation mode. Corrective measures were applied for a month. The effectiveness of these measures was evaluated by making 8 new G2 cross-sectional studies of the same type. Two hundred forty-eight G1 and 250 G2 recordings were made. The G2 studies revealed a generalized reduction in errors for all parameters. We concluded that the corrective measures were effective so these indicators were included in the monitoring of risk areas in the unit quality control program.

Critical Care↗