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Biomedical subjects

M Boasson

Publications and source records attributed to M Boasson.

At least 55 records · Page 3Linked to original sources
PubMed1980

[Calcium metabolism study performed by means of Ca-45 in bone diseases and idiopathic hypercalciuria].

The authors analyse the results obtained during 54 radioisotope investigations using 45Ca in 13 cases of idiopathic hypercalciuria, 12 cases of osteoporosis, 3 cases of Paget's disease, and 2 cases of osteomalacia including one of Fanconi's disease in an adult. In 12 patients, repetition of the radio-isotope test two, three or four times; permitted the authors to study the effects of the treatments administered: calcitonin, phosphate, vitamin D, parathormon, oestrogen. Calcitonin increases intestinal absorption and reduces bone reabsorption and also accretion. Phosphate greatly increases accretion and bone reabsorption in vitamin-resistant osteomalacia of adults. The synthetic fragment 1--34 of human parathormone increases accretion and reabsorption but does not modify the calcium balance. The addition of estrogen reduces reabsorption and slightly increases accretion in two osteoporotic patients producing a positive calcium balance. This method of investigation is of great interest to assess the effects of a drug on calcium metabolism and on the two processes of bone remodelling.

Aged↗
PubMed1978

[Vitamin-resistant osteomalacias of hepatic origin in the adult].

The authors report two cases of vitamin resistant osteomalacia in an adult connected with an apparent inability of the liver to hydroxylate vitamin D. One of the cases showed a case of pseudo-hypo parathyroidism of type II, reversible by the administration of calcium. The other case demonstrated vertebral hyperossification. Treated with 25 hydroxycholecalciferol in physiological dosage an improvement in the clinical, biochemical and histological states resulted.

Female↗
PubMedDate not supplied

[Hematopoietic growth factors].

Haematopoietic growth factors play a very important role in the proliferation and maturation of medullary cells. To date, about fifteen of these factors have been characterized and are known to act either on the most immature progenitors, or on the proliferation compartment, or on already mature cells. In fact, myeloid lines depend on complex interactions between these various inductors. All these inductors are made of glycoproteins, and many of them are continuously located on the long arm of chromosome 5, but they do not represent a family of genes. Their receptors are not limited to normal haematopoietic cells, and this lack of selectivity accounts for certain side-effects observed in clinical use and for the (theoretical) risk associated with their use in the treatment of some malignant blood diseases or even solid tumours.

Cytokines↗