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Biomedical subjects

M Bodó

Publications and source records attributed to M Bodó.

At least 37 records · Page 2Linked to original sources

Endocervical cytology: characterization of the cells by image analyzer.

Authors report on 359 patient's endocervical smears taken by cytobrush. Stromby's endocervical brush did not cause bleeding disturbance or preventing colposcopic examination. The smears contained numerous, well evaluable squamous and endocervical cells. Out of seven cytologically positive cases three proved to be negative by colposcopy. Histology, however, confirmed the cytological diagnosis. Cytology was followed by histology in 42 cases. Cytological and histological diagnoses were compared, there was one false negative. For the more precise characterization of endocervical cells 13 features were measured by a Robotron type image analyzer and the results were statistically analyzed. The respective cell groups can be separated from each other by morphometric and densitometric parameters. Results of this study have produced a data base that can be extended further on. It may give help in case of differential diagnostic problems since it is capable of distinguishing certain cell groups, consequently these data can be incorporated into a diagnostic program.

Cervix Uteri↗

Clear cell thyroid cancer--undifferentiated type--an immunohistochemical and electron microscopical study.

Two cases of clear cell thyroid cancer are described. In both tumors immunohistochemical methods detected the presence of intracytoplasmic thyroglobulin that confirmed the follicular origin. Simultaneously performed electron microscopic studies visualized the accumulation of smooth surfaced, membrane coated vesicles of varying size in the cytoplasm. Bad prognosis predicted on the base of undifferentiated histological structure was confirmed by extended hematogenic metastases.

Adenocarcinoma↗

Diagnostic value of infrared thermography in breast cancer, and in proliferative and non proliferative mastopathies.

The authors present the results of breast examinations in 201 female patients controlled by cytology and histology. Based on their results obtained by an AGA 680 type infrared thermography, their conclusion was that the method is primarily suitable for the examination of biological thermogenesis, one of the functional characteristics of tumours. Some T1 breast cancer of the same histological type are thermographically "silent", i.e. display no pathological alterations. Thermographical signs characteristic of carcinomas are to be found only in 60-70% of the cases. It is explained by the biological heterogeneity of tumours, i.e. the amount of heat generated by the metabolic processes of the different carcinomas is not equal, as well as they are different in vascularization and as a consequence of it in their heat conduction parameters. Similar reasons explain the appearance of different thermographic patterns--negative or characteristic of cancerous alterations--in proliferative mastopathies.

Breast Diseases↗

Branchiogenic carcinoma (malignant branchioma).

The authors describe the characteristics of branchiogenic carcinoma as that of a pathological entity on the occasion of reporting four cases. The clinical course of the disease and the cytological and histological features are discussed on the basis of our observations and literature data. The authors stress the importance of careful and repeated clinical examinations, which exclude the possibility of a primary tumor of other localization, in establishing the diagnosis of branchiogenic carcinoma.

Adult↗

Aspiration cytodiagnostics of breast tumours.

Aspiration cytology has been performed in 2,180 cases of breast alterations. Cytological examination was followed by histological control in 967 cases. Diagnostic value (sensitivity) of the method proved to be as high as 83%. As a matter of principle, the technique cannot substitute histology. Using in combination with other clinical diagnostic measures like palpation, mammography, xeromammography, thermography the diagnostic possibilities are multipled. This preoperative morphological test of orientatory value which is rapid, cheap and painless and devoid of any complications is worth of widespread use. According to the authors opinion its routine application in the clinical practice is highly desirable.

Adenocarcinoma, Mucinous↗

Training of prescreening cytotechnicians. A report on 10-year experience.

Institutional training of prescreening cytotechnicians started in 1972 in the Research Institute of Oncopathology, Budapest. Up to 1983 ten classes, i.e. 230 students have been trained. Authors acknowledge the good achievements of their students and state that the diagnostic reliability of the qualified cytotechnicians has been recognized by professionals. Their activity resulted in a considerably increased number of screenings and recognized cervical cancers. In 1964 merely 25 600 examinations, whereas in 1982 altogether 1 030 000 examinations were performed. Cervical cancers announced in 1978 were 597, but in 1982 this number rose to 1022, being 661 (66%) in stage 0. A so-called Cervix Program based on the activity of cytotechnicians has been initiated by the Hungarian Ministry of Health. In view of the authors' ten-year experience the execution of this enormous enterprise seems possible.

Cytodiagnosis↗

[Angioimmunoblastic lymphadenopathy].

Cytological, histological and ultrastructural characteristics of a cose of an extranodal and nodal angioimmunoblastic lymphadenopathy persisting during several years are given. Angiomatous proliferation in the case reported seemed to be identical both in the lymph node and in the cutaneous infiltration. Types of cells seen in the angioimmunablastic lymphadenopathy did not differ from those of other immunoreactive processes. In the extranodal infiltrates in addition to other phenomena thickening of the immunological techniques decrease of the natural cytotoxicity and the number of T-lymphocytes could be observed.

Autoantibodies↗