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M Bodian

Publications and source records attributed to M Bodian.

10 recordsLinked to original sources

Does conjunctival resection in ptosis surgery lead to dry-eye syndrome?

On collating the results of four ophthalmic surgeons after conjunctivolevator resection in ptosis surgery we found no instance of dry-eye syndrome. Our conclusions were based on clinical findings and Schirmer testing after many hundreds of such operations. This study was undertaken because some ophthalmic surgeons had speculated that removal of conjunctiva in this type of surgery would lead to keratoconjunctivitis sicca. Despite prolonged follow-up (as much as 30 years), this has not occurred. All contributing surgeons expressed satisfaction with conjunctivolevator resection in ptosis surgery on selected cases.

Adolescent

Repair of occluded lower canaliculus.

Epiphora resulting from traumatic occlusion of the inferior canaliculus has long been a vexing problem. A simple operation to cure some of these cases consists of unroofing the proximal portion of the canaliculus with use of a smooth-tipped pigtail probe passed from above as a guide. Prerequisites for the operation are a patent superior canaliculus, sac, and proximal segment of the inferior canaliculus. Epiphora was corrected in five of seven eyes with this surgery.

Adult

A tarsal resection procedure for senile entropion with lid retraction.

1. A method of tarso-conjunctival resection for correction of spastic entropion associated with lid retraction has been presented which prevents a) the presence of suture knots against the cornea, b) localized trichiasis, and c) tissue reaction to absorbable sutures. 2. These advantages are achieved through the use of several figure-of-8 silk sutures which are tied on the skin surface. 3. By keeping the apex of the excised triangle of tarsus 2 mm below the lid margin trichiasis may be avoided. 4. Twelve operations have been followed for 1 to 6 years. The retraction and entropion were markedly improved in eleven lids. One under-correction resulted. There were no other complications.

Entropion

A revised Fasanella-Servat ptosis operation.

The Fasanella-Servat operation for ptosis has had several modifications of suture placement. The present method utilized 5-0 nylon which traverses the cut edges as a running mattress suture. The ends of the suture are fixed on the skin surface with rubber bolsters. The suture is removed in 10 days. The advantages are: (1) no suture knots on the corneal surface; (2) ease of placement; (3) minimal tissue reaction; (4) the suture is removed; and (5) ease of suture removal.

Adult

[The campaign against leprosy in an urban African environment: problems encountered at the level of case-finding and of monitoring of patients in Dakar].

The authors first explain the main epidemiological parameters of leprosy in Dakar, their evolution and their differences with those of the rest of the country. The second part deals with case finding and reveals the essential importance of the voluntary detection which appears as rather early: 3.5% of second degree physical disabilities; 37% of monomacular lesions in the paucibacillary lesions. The third part explains the problems encountered on leprosy control with the study of a cohort of 241 patients: 64% were missing in 4 years and half of them during the first year. At the end of 4 to 6 years, only 19% of the patients had a regular attendance at treatment. The defects are significantly more frequent with the male patients, and with the people who have been residing in Dakar for less than two years. In the suggested solutions, the authors insist on the necessity to adopt short multidrug protocols and to make health education for patients so that they care about case finding with their contacts.

Adolescent

[Multi-drug therapy trials for leprosy in Senegal: first observations relative to liver tolerance of multibacillary patients. Therapeutic consequences].

The authors have studied tolerance of multibacillary patients to 4 MDT regimens. These 4 regimens consist of: One supervised part in which RMP-ETH combination in once-monthly administered; furthermore, in 2 of these regimens, is included one "starter phase" with daily doses of that combination for 2 months. One self-administered part during which CLO is associated either to DDS for new cases, or to ETH for relapses. Clinical Supervision: Out to 310 multibacillary patients, 7 cases of hepatitis with or without icterus, but no death due to the treatment. Interruptions of MDT have been temporary and have been observed in 0.9 to 5.6% of the patients according to the therapeutic regimen. Checking SGOT: The SGOT were abnormally high in 16.3% of the patients before treatment. These pre-existing liver damages do not favour the appearance of intolerance disorders. During MDT, abnormal increases in SGOT are observed in 27% of the patients but there is no exact correlation between the absorbed doses of ETH and the frequency in SGOT increases. The clinical or biological evidence of liver damages occur rather early (1st, 2nd month) in regimens with "starter phase", and later (4th-8th month) in those without "starter phase". But introduction of "Starter phase" does not increase the global frequency of such intolerance accidents. ETH combined with RMP, must be used under steady clinical and biological supervision. Recalling the results of a previous survey, the authors consider that a long duration of MDT is not necessary. For the multibacillary leprosy treatment, they propose a diphasic regimen, more easily applicable in the field than the WHO protocols. In this diphasic regimen, the only part which must be supervised is the initial "starter phase" of 2 month. It consists of daily administration of 3 antibacillary drug among which RMP and ETH. The second phase is a relay treatment using 2 drugs, CLO combined with DDS or ETH, self-administered until smear negativity.

Adolescent

[Resistance of Mycobacterium leprae to dapsone and rifampicin: apropos of a survey carried out in the Cape Verde region (Senegal)].

Since 1983, primary resistance of M. leprae to DDS and rifampicin has been evaluated in new cases of lepromatous leprosy observed in the Cap-Verde region in Senegal. Out of the 13 strains isolated, 10 (77%) have been found resistant to DDS, 7 at low level, 2 at intermediate level, 1 at high level; all of them have been found sensible to rifampicin. Similar results have been obtained with 57 strains isolated from patients not yet treated coming from different geographical areas, seeing that 37, i.e. 65%, were resistant to DDS, 27 at low level, 5 at intermediate level and 5 at high level; all of them were sensible to rifampicin. Level of resistance to DDS is very different in case of acquired resistance. In 69 lepromatous patients treated for more than 5 years and showing a relapse, M. leprae was 62 times, i.e. 90%, resistant to DDS, 6 times at low level, 21 at intermediate level and 35 at high level; in addition, 13 times M. leprae was resistant to rifampicin. In order to avoid and to solve problems set by resistance of M. leprae to antibiotics, strict application of polychemotherapy of leprosy is compulsory.

Dapsone

[A trial of polychemotherapy of leprosy in the Dakar region. Initial observations on the acceptability of the protocols used].

Since 1982, in Dakar, a controlled essay tests the suitability of several short protocols of multidrug therapy (MDT), some of them being close to those advised by the WHO, others showing a starter stage of a two month daily MDT. In three years, 198 paucibacillary and 123 multibacillary patients have been treated. The short duration of these treatments leads to an important decrease in the load of the Department. The total rate of those who have not attended for the treatment is of 15.2% whereas it was of 52% with DDS monotherapy for a similar treatment duration. Those who gave up don't seem to live in Dakar. To judge by the diligence of the patients, the compliance seems excellent even for the protocols requiring a daily dose of ethionamide: 95% of paucibacillary, 76% of multibacillary patients have maximal attendance. The authors think that any MDT program: must be preceded by a retraining of staffs; must give a priority to the health education of the patients; must involve a home patient search for system.

Adolescent