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Biomedical subjects

M Bongard

Publications and source records attributed to M Bongard.

6 recordsLinked to original sources

Hyperfine spectrum of RbCl.

The molecular beam electric resonance technique has been used to conduct a high precision examination of the hyperfine spectrum of the four isotopomers of RbCl. Coupling constants for the nuclear electric quadrupole interactions, the spin-rotation interactions, the tensor and scalar spin-spin interactions, and a rubidium nuclear octupole interaction, and their dependence on vibrational and rotational states have been determined. The dominant interaction, the rubidium nuclear electric quadrupole interaction, shows a small shift with substitution of the chlorine isotope.

Journal Article↗

Nuclear electric quadrupole moments of Rb from the hyperfine spectrum of RbF.

The molecular beam electric resonance technique has been used to examine the hyperfine spectrum of RbF. The Rb nuclear electric quadrupole interaction, the spin-rotation interactions, and tensor and scalar spin-spin interactions have been measured for both Rb isotopes, including their dependence on vibrational and rotational states. Transition frequencies have been determined to a precision of better than 1 Hz in many cases. The magnetic interactions in the two isotopomers are consistent with what is expected from the known masses and magnetic dipole moments. In the case of the Rb nuclear electric quadrupole interaction, adjustments have been made for a small isotopomer shift, and for the ratio of the effective nuclear electric quadrupole moments, Q(87Rb)Q(85Rb) = 0.483 830 1+/-0.000 001 8. The effective quadrupole interaction includes a pseudoquadrupole interaction that may be significant at this level of precision, but cannot be distinguished experimentally.

Journal Article↗

Development of a cortical visual neuroprosthesis for the blind: the relevance of neuroplasticity.

Clinical applications such as artificial vision require extraordinary, diverse, lengthy and intimate collaborations among basic scientists, engineers and clinicians. In this review, we present the state of research on a visual neuroprosthesis designed to interface with the occipital visual cortex as a means through which a limited, but useful, visual sense could be restored in profoundly blind individuals. We review the most important physiological principles regarding this neuroprosthetic approach and emphasize the role of neural plasticity in order to achieve desired behavioral outcomes. While full restoration of fine detailed vision with current technology is unlikely in the immediate near future, the discrimination of shapes and the localization of objects should be possible allowing blind subjects to navigate in a unfamiliar environment and perhaps even to read enlarged text. Continued research and development in neuroprosthesis technology will likely result in a substantial improvement in the quality of life of blind and visually impaired individuals.

Artificial Intelligence↗

An anomaly in the isotopomer shift of the hyperfine spectrum of LiI.

A high-precision examination of the hyperfine spectrum of 6LiI in comparison with 7LiI shows a shift in the iodine nuclear electric quadrupole moment that cannot be accounted for by a model in which the electric field gradient at the iodine site is assumed to depend only upon the internuclear distance between Li and I. The other hyperfine interactions are consistent between the two isotopomers, including the previously reported electric hexadecapole interaction of the iodine nucleus.

Journal Article↗

Population coding of motion patterns in the early visual system.

Using extracellular recordings and computational modeling, we study the responses of a population of turtle (Pseudemys scripta elegans) retinal ganglion cells to different motion patterns. The onset of motion of a bright bar is signaled by a rise of the population activity that occurs within less than 100 ms. Correspondingly, more complex stimulus movement patterns are reflected by rapid variations of the firing rate of the retinal ganglion cell population. This behavior is reproduced by a computational model that generates ganglion cell activity from the spatio-temporal stimulus pattern using a Wiener model complemented by a non-linear contrast gain control feedback loop responsible for the sharp transients in response to motion onset. This study demonstrates that contrast gain control strongly influences the temporal course of retinal population activity, and thereby plays a major role in the formation of a population code for stimulus movement patterns.

Animals↗