[Mucinous adenocarcinoma of the urachus. Clinical and radiologic aspects of a case].
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Adenocarcinoma, Mucinous↗
Biomedical subjects
M Borrelli
Publications and source records attributed to M Borrelli.
Growth-associated gene expression is not constant in cells traversing G-1 after exiting mitosis.
Analysis of gene expression following stimulation of growth-arrested cells has been the main approach for identification of growth-associated genes. Since the activation of these gene sequences is dependent on both the stimulatory agent and the state of quiescence of the cell, the activation and role of the same genes may be entirely different in non-growth arrested, actively proliferating cells. We have addressed the question of growth-associated gene expression during active growth by analyzing gene expression during G-1 of cells which have just exited mitosis without first leaving the cell cycle. We were able to isolate, by a non-inductive, drug free system, a population of highly synchronized Swiss 3T3 cells within mitosis (greater than 90%) in numbers sufficient to determine the pattern of expression of a large number of representative growth-associated genes. Our results show that after replating the mitotic cells into conditioned medium: (1) growth-associated gene expression is not constant during G-1 of actively proliferating cells, and (2) while a number of genes (e.g., JE, c-myc, ODC, p53, and histone) exhibited patterns of expression similar to that reported in the quiescent systems, others (e.g., nur-77, vimentin, calcyclin) exhibited patterns which were completely different. From these results, we can begin to construct a temporal map of G-1 progression during active growth.
Animals↗
Ureteral necrosis in dermatomyositis.
We describe a child with dermatomyositis and calcified necrosis in the middle third of both ureters. Histopathological examination showed vasculitis associated with ureteral necrosis and calcification. These findings together with a similar previous report in the literature have prompted us to correlate dermatomyositis in childhood with ureteral necrosis and to anticipate specifically a lesion in the middle third of the ureter because of the relative lack of blood flow in that segment.
Child↗
Blood loss during and following transurethral resection.
Blood loss measurement in transurethral prostatic surgery (TUR) has been studied with the following objectives: (1) to measure the total lost volume (during surgery and 48 hours postoperatively); (2) to compare surgical bleeding and coagulogram alterations in benign prostatic hypertrophy (BPH) and prostatic carcinoma (CaP); (3) to establish the relationship between blood loss, duration of the procedure, and amount of resected tissue. The method of Jansen was used to measure blood loss, and the "coagulogram" included the following parameters: hematrocrit; prothrombin, recalcification, thrombin, and partial thromboplastin times; fibrinogen; platelets and fibrin split products. The study is based on TUR performed on 75 patients from whom a mean weight of 25.68 grams was resected resulting in a mean total bleeding volume of 305 ml. Blood loss over 400 ml was associated with surgical durations of 60 minutes or with resection of over 40 grams of tissue. There was a slight tendency for fibrinolysis in prostatic cancer, which could explain the relatively higher amount of blood loss observed in these cases.
Aged↗
Segmental priapism.
A case report of a 27-year-old male with segmental priapism of the left proximal corpus cavernosum is presented. Treatment consisted in evacuation and irrigation of the corpus.
Adult↗
[Stenosis of the renal artery as a cause of acute renal insufficiency after transplantation].
Eight cases of kidney transplant recipients that developed acute renal failure are described. Arterial renal stenosis was responsabilised for the ARF. One patient was submitted to transluminar angioplasty without success and then operated. This technique was the successful treatment in another patient. Four patient were submitted to surgical correction as first therapeutic approach. Two patients received no specific treatment. From the six treated patients five had good evolution.
Acute Kidney Injury↗
[Selective arteriography in fractures of the femur head].
The choice between conservative and radical operation in case of femoral neck fractures is very important because it is the determining factor for a successful therapy. In case of epiphysial necrosis, an endoprosthesis as well as an osteosynthesis will be carried out. Selective arteriography of the medial circumflex artery represents the most reliable study to establish, immediately after the fracture, the possible presence of a post-traumatic ischemic necrosis. Angiography, as a reliable diagnostic tool, has to be carried out in the most selective way and needs the image subtraction technique. The authors report their preliminary results on the reliability of angiography in the femoral epiphyseal ischemic necrosis diagnosed by comparing the results of angiography with the Wood light test carried out on the surgically removed femoral head.
Adult↗
[Culture studies of the bile during transhepatic cholangiography].
A bacterial examination was carried out on bile taken from 119 patients undergoing transhepatic percutaneous cholangiography (P.T.C.) due to biliary obstruction. Bacteria were found in 36.9% of cases, with greater frequency in cases of benign obstructions (69.6%) than malignant obstructions (27.2%). The extent of obstruction was found to make no difference (stenotic or obstructive). These results therefore confirm that a risk of infectious complications during P.T.C. exist. Susceptibility studies carried out on bile bacteria showed gentamycin to be the most effective antibiotic in the prevention and treatment of infection in these cases.
Adult↗
Sacral agenesis: why is it so frequently misdiagnosed?
Thirty-four patients with sacral agenesis were seen from 1954 to 1983, cases of meningomyelocele excluded. Five recognizable and consistent patterns of bone malformation were identified. Urodynamic examinations were done in 10 of the 34 patients. Their evaluation and response to treatment are analyzed; we tried to determine and establish the possible causes for its late diagnosis and consequences regarding the upper urinary tract.
Abnormalities, Multiple↗
[Xeroangiography. Technical principals and applied developments].
The physical patterns ruling the information of a xeroradiographic image allow the visualization of the arterial system with a lower concentration of contrast medium. So you can visualize the arterial branches both with intravenous injection of the usual angiographic concentration of contrast medium or with intraarterial injection of diluted contrast medium at a very low concentration. A prerequisite to successful xeroangiography was the commercial diffusion of a changer for xerox cassettes allowing several exposures according to standardized programs.
Angiography↗
[Transvenous xeroangiography of arteriovenous fistulas of patients undergoing periodic hemodialysis].
Xeroradiography allows visualisation of the arterial system after intravenous injection of contrast media. This method has proved particularly useful for diagnosis of changes in the arteriovenous fistulas of 20 patients on chronic haemodialysis. In all cases transvenous xeroangiography gave information about morphologic alterations of vessels and soft tissues. Among the commonly used angiographic methods, transvenous xeroangiography appears the technique of choice.
Aged↗
[Anatrophic nephrotomy for treatment renal staghorn lithiasis (author's transl)].
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Bacterial Infections↗
[Renal transplant in children].
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Adolescent↗
[Pregnancy after renal transplant].
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Abnormalities, Drug-Induced↗
Cavernospongiosum shunt in management of priapism: is it a reliable method?
The efficiency of cavernospongiosum shunt in the management of priapism was evaluated in 10 patients. Technical details such as the "Z" perineal incision and the opening followed by closure of the contralateral corpus cavernosum, at the time of corpora evacuation, can improve the local exposure and permits a more complete drainage of the corpus cavernosum, but did not improve our results when they were compared with other techniques for treatment of priapism. Penile flaccidity and preservation of sexual potency occurred in 6 (60%) and 5 (50%) patients, respectively, and no surgical complications were observed. Immediate penile flaccidity and regaining of physiologic erection were, however, not complete even in the successfully treated patients. The cavernospongiosum shunt does not seem to represent the definitive form of treating priapism. New knowledge about mechanisms involved in priapism has to be obtained, in order to improve the approach and the prognosis of this disabling condition.
Adolescent↗
Bladder training and surgical correction of vesicoureteral reflux: useful association.
18 children, from 1 year of age to 15, presenting lower motor neuron bladder (myelomeningocele) were studied. All had overflow incontinence and urinary infection resistant to all trials of treatment, attributed to severe vesicoureteral reflux. The failure of training on bladder emptying for urinary infection control and/or the severity of reflux and its consequences over upper urinary tract, motivated the reflux surgical correction associated to bladder training as a first step alternative treatment to urinary diversion.
Adolescent↗
Urinary incontinence: two cases of electronic stimulation after failing the Leadbetter technique.
Two cases of urinary incontinence treated by electrical stimulation after failing the Leadbetter technique are presented. Both were first seen bearing imperforated anus. They suffered several operations for correcting this pathology and further attempting to relieve complete urinary incontinence. After a trial with intrarectal stimulation one of them received an implant. The other continued to use the anal plug. In both cases the result has been satisfactory. Cine radiological documentation of the sphincteric action of the stimulated muscles was performed.
Child↗