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Biomedical subjects

M Borzemska

Publications and source records attributed to M Borzemska.

4 recordsLinked to original sources
PubMed1979

[Behavior of glycoproteins and blood serum proteins in rats after PVC implantation].

Determination of soluble protein level and bound sialic acid in 0,15 M SSA (seromucoid) as well as of protein levels and total sialic acid (NANA) were made both in blood serum and serous fluid. These tests were performed before and after subcutaneous and intra-abdominal implantation of different PVC samples. The subcutaneous implantation of samples caused the appearance of serous fluid and subsequently inflammation characterized by an increase of levels of sialic acid and seromucoid--the so-called "acute protein reaction". There were also observed the increased electrophoretic alpha 1, alpha 2 and beta globulin levels. Intra-abdominal implantation caused a decrease in the sialic acid level. Also the albumin fraction decreased but the concentration of the alpha 1 globulin fraction stayed within normal limits.

Animals↗
PubMed1978

[Comparative study of methods of estimating the hemolytic activity of aqueous plastic extracts. Preliminary report].

The examination of haemolytic activity of aqueous plastic extracts represents one of the method to evaluate plastics of medical grade. In own examinations different methods were used to estimate the haemolytic activity of aqueous extracts of some toxic materials, e.g. technical gums, epoxides, also silicone resins, which are admitted to medical use. On the basis of literature and own examinations the most sensitive method to estimate the haemolytic test was found to be the method after the Japanese Pharmacopoeia. The degree of haemolysis due to the water extracts both of technical gums and epoxides was found to be significantly different from the norms. The silicone resins fulfilled the demands for medical materials. On the basis of the results, the method described in the Japanese Pharmacopoeia was accepted as an appropriate test for evaluation of haemolytic activity of aqueous plastic extracts designed to blood contact or to implantation.

Hemolysis↗
PubMed1978

Basic studies on autogenized and lysophilized vascular prostheses.

In an effort to improve vascular prostheses, basic studies on tissue-alloplastic prostheses according to a new conception were performed. A medical polyester yarn was used for the construction of three types of prostheses with different mesh and high porosity. The prostheses were autogenized on silicon rods and then lyophilized, resulting in their full intraoperative impermeability, but high biological permeability and antithrombogenicity. Vascular prostheses of this type fulfill many of the requirements of a so-called ideal prosthesis. Analysis of the test examinations provides a basis for elaborating principles for the preparation and production of new tissue-alloplastic prostheses for clinical purposes.

Bacterial Infections↗