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Biomedical subjects

M Boscq

Publications and source records attributed to M Boscq.

14 recordsLinked to original sources
PubMed2006

[Neurofibromatosis type 1 complications in the pediatric age: follow-up of a hundred cases].

UNLABELLED: Neurofibromatosis 1 (NF1) is a frequent genetic disease. Diagnostic criterias were established in 1988. The patients can exhibit various and unpredictable complications. OBJECTIVES: To check the efficiency of a coordinated follow-up in specialized multidisciplinary centers providing a higher quality of management and to have a better knowledge of the complications including their true frequencies. POPULATION AND METHODS: We report a serie of 100 NF1 children who were followed-up during 4 years in a specialized center at the Tours University Hospital. Three hospital check-up at 2-5, 6-7, 14-15 years of age were performed as well as an annual physical examination. RESULTS: In our serie, the mean age was 7.8 years old with a sex ratio of 1. The mean age at diagnosis was 3.8 years old and the main diagnosis criteria were the café-au-lait spots and the family history for 80% of the patients. The optic nerve glioma has a low frequency of 5%. Learning disabilities clearly represent the most frequent complication (46% of the patients). CONCLUSION: An early detection of these difficulties is a priority for the appropriate management of these children.

Adolescent↗
PubMed2006

[Pericochlear hypodensity on CT: normal variant in childhood].

PURPOSE: Evaluation of the prevalence of a pericochlear hypodensity on CT in children. Materials and methods. This study correlates the findings on temporal bone CT to the indications for CT (headache, trauma). Helical CT acquisitions using 0,5 mm, 0,6 mm or 0,75 mm slice thickness according to the material available, with multiplanar reconstructions. Only patients with significant pericochlear hypodensity, larger or equal to 0,4 mm, were taken into account, and the curvilinear or nodular nature of the lesion on axial and coronal sections was recorded. RESULTS: A pericochlear hypodensity was identified in nearly 40% of cases. There was no population predominence according to the indication for the CT. The curvilinear type was more frequent on coronal images, with unilateral and bilateral involvement being equally frequent. There was no significant difference according to the sex. Patients of all ages showed lesions, from newborns to adolescents, with increased frequency in childhood. CONCLUSION: This study confirms a high prevalence of pericochlear hypodensity in a paediatric population, without clinical correlation, which requires prudence when interpreting the significance of this CT sign commonly described in association with pericochlear otosclerosis and the pericochlear form of osteogenesis imperfecta.

Adolescent↗
PubMed2003

[Reduction of acute intestinal intussusception: when and how?].

After sonographic diagnosis, non-surgical therapy for intussusception in children uses pneumatic or hydrostatic (barium or water soluble) reduction. The purpose of this paper, in the light of our experience, is to answer the questions raised by general radiologists in emergency activity about the technique, indications, sedation and risks.

Acute Disease↗
PubMed1998

Iodixanol in paediatric excretory urography: efficiency and safety compared to iohexol.

BACKGROUND: Iodixanol (Visipaque, Nycomed Imaging AS, Oslo, Norway) is a new non-ionic and isotonic X-ray contrast medium. OBJECTIVE: To assess its safety and efficacy for paediatric excretory urography. MATERIALS AND METHODS: A three-centre trial in which 72 patients were randomised into three parallel groups: iodixanol 270 mgI/ml, iodixanol 320 mgI/ml and iohexol 300 mgI/ml (Omnipaque, Nycomed Imaging, Oslo, Norway). Doses ranging from 1 to 3 ml/kg never exceeded 50 ml. Pulse rate and blood pressure were recorded before, during, and after the examination. Adverse events, including injection associated discomfort, were recorded during and up to 24 h after the examination. The diagnostic quality of the urograms was assessed on a four-level scale. RESULTS: No serious adverse event occurred in any of the three groups. One patient who was given iodixanol 270 mgI/ml, three who received iodixanol 320 mgI/ml, and one who received iohexol 300 mgI/ml experienced transient adverse events. More than 80 % of the urograms in all three groups were rated "good" or "excellent". CONCLUSION: Iodixanol, either 270 mgI/ml or 320 mgI/ml, is well tolerated and efficacious for excretory urography in children.

Adolescent↗
PubMed1990

Accidental lidocaine overdosage in an infant.

A one month old child inadvertently received an intravenous bolus injection of 50 mg of lidocaine instead of contrast iodine. The clinical picture comprised collapse, respiratory arrest, convulsions and coma. The calculated maximum level of lidocaine was 5.39 mg/l. The recovery was complete. The toxicity of lidocaine is discussed.

Drug Overdose↗
PubMed1987

Embryonal rhabdomyosarcoma of the biliary tree in children: a case report.

Embryonal rhabdomyosarcoma (ERS) in children is a very rare tumor. Jaundice is the capital symptom. Diagnosis can be made by echography, which shows echogenic formations without posterior conic shadows in a dilated biliary duct. The prognosis is bleak in spite of the combination of surgery, radiotherapy and chemotherapy.

Bile Duct Neoplasms↗
PubMed1986

[Acute intestinal intussusception in infants and children and abdominal ultrasonography].

Ultrasound imaging findings of the invaginated bud are described in 60 young children referred with a suspected acute intestinal intussusception over a period of 5 months. An initial group of 28 children were examined by ultrasonography and a barium enema for diagnostic and possible therapeutic purposes. The second series of 32 children were a therapeutic enema only when ultrasound images provided a positive diagnosis. The method is considered to be a reliable one requiring less medication, and has the principal advantage of suppression of the need for diagnostic barium enema.

Abdomen↗
PubMed1977

[Double contrast hypotonic duodenography].

Double contrast hypotonic duodenography, as carried out by the authors, is a simple and rapid examination, suitable for routine use. At the same time, it includes a double contrast study of the oesophagus and stomach. The normal appearance is easily analysed, in particular that of the great caronculus. It is a selective examination of the duodenal outline, playing an essential role in the detection of lesions of the latter as well as in adjacent organs which may alter its shape. It provides only a suggestion as to aetiology and must therefore be completed, when appropriate, by other studies.

Ampulla of Vater↗
PubMedDate not supplied

[First urinary infection in infants aged less than 3 months. Diagnostic and therapeutic aspects from 44 cases].

While studying retrospectively 44 cases in infants less than 3 months with urinary tract infection, clinical, bacteriological and radiological aspects have been analyzed. Clinical symptomatology were chiefly fever and digestive symptoms (anorexia, vomiting) associated with poor weight gain. Among the causative bacteria, E. coli was the most frequent (88%) with ampicillin resistance in 26% of them. Diagnosis difficulties associated with urine collection with a bag, frequently contaminated, have to be emphasized. It is therefore necessary, except in case of emergency to repeat urine collection before treatment. Among 35 infants investigated radiologically, the urinary tract was abnormal in 46% (48% boys and 40% girls). The localization of the abnormality was upper in 16% and lower (reflux) in 43%. Ampicillin alone or associated with an aminoglycoside was the most common treatment (33 cases). Urine sterilization has always been obtained.

Female↗