Other special considerations in assessing DC-ART: The need for patient stratification.
Given the heterogeneity of rheumatoid arthritis (RA), even in disease of the same duration, it seems likely that some therapeutic regimens will satisfy DC-ART criteria to different degrees in different strata of patients with RA. Since it entails its own problems, it is recommended that the value and feasibility of stratification be evaluated before any attempt to design a DC-ART trial.
Antirheumatic Agents↗