Biomedical subjects

M Bosio

Publications and source records attributed to M Bosio.

23 records · Page 2Linked to original sources

PubMed1979

A comparative study of poly(glycolic acid) and catgut as suture materials. Histomorphology and mechanical properties.

The "quality" of poly(glycolic acid) as an absorbable suture material was investigated in comparison with catgut. Tissue reactions to poly(glycolic acid) and plain catgut were examined histomorphologically at different time intervals after implantation in rats, and compared. Four mechanical properties were also examined as relevant quality factors: elastic stiffness, tensile strength, toughness, and percent elongation at rupture of the suture material per se (unknotted). The variation of these properties in poly(glycolic acid) implants was followed since their insertion in the tissues. Histological behavior and mechanical properties appear to be more closely correlated in the case of poly(glycolic acid) than in the case of catgut, as a consequence of a greater regularity of tissue reaction towards the synthetic material. Both tissue reaction and tensile properties variation are independent of size in the case of the braided poly(glycolic acid) sutures examined. Elastic stiffness and tensile strength decrease steadily in time; toughness and ultimate elongation display an increase up to a maximum within one day since implantation, and then decrease.

Abdominal Muscles↗

PubMed1975

[Glycolic acid/polymer as suture material].

Tissue reactions to polyglycol acid and plain catgut threads were compared. The second part of the paper deals with changes in the mechanical properties of the polymer. Their reduction after insertion in tissues was proportionally equal for threads of different sizes. This finding is explicable histologically, since it can be shown that cell and humoral attack of the single filaments is homogenous throughout the entire cross-section of the thread.

Abdominal Muscles↗

PubMedDate not supplied

[Quality and efficiency of the Health Service in the Italian Region of Lombardy].

The Regional Law No. 31 of 1997 has revised the Lombardy Health Service as a whole, separating "providers", credited Public and Private Health Institutions, from "purchasers", Local Health Agencies. To this purpose, the improvement of the quality of assistance has been enhanced through an accreditation process aimed at implementing second level regional requirements considered as being necessary for carrying out effective treatment and meeting patient needs. Training, implementation and evaluation of quality service within Health Institutions have been carried out with the assistance of the Regional Observatory on the Quality of Health Service, which helped to identify initial intervention areas, define process indicators, activities and outcomes and verify patient satisfaction, all this to improve performance, reduce risks and control costs. To fully develop the Institutions in the accreditation process, the complex and difficult aspect of health care quality has been more extensively and deeply dealt with by adopting an "Excellence accreditation" model in cooperation with the Joint Commission International Accreditation and by experimenting with Professional accreditation supported by Scientific Societies to further contribute to the development of technical skills and knowledge. The Quality Project carried out so far is based on the integration of various projects, which will be the object of practical interventions by the General Health Direction. All the information and results gathered from this project will be very helpful in finding solutions that will enable all Health Institutions in Lombardy to reach an adequate level of quality.

Accreditation↗

PubMedDate not supplied

[Transient hyperphosphatasemia in childhood. 4 new cases and review of the literature].

Transient hyperphosphatasemia of infancy is a biochemical syndrome characterized by a striking, transient increase in serum alkaline phosphatase in children without any evidence of bone or liver disease and of a familial occurrence. The abnormal isoenzyme pattern frequently observed in this syndrome may represent an excessively sialylated form of the liver isoenzyme, not normally removed from circulation. Here are described four new cases of this syndrome, followed biochemically and clinically until normalization of the serum abnormalities; a review of literature is also presented.

Alkaline Phosphatase↗

PubMedDate not supplied

[Paralysis of the sciatic nerve and gluteal necrosis caused by umbilical artery catheterization in a newborn infant. Description of a case followed for 6 years].

A premature newborn developed left sciatic palsy and gluteal necrosis following umbilical artery catheterization. A six-year follow-up revealed an one-cm shortening of the left leg and foot, with an appreciable functional recovery. In connection with this rare thromboembolic complication of catheterization, we reviewed the Literature about the pathogenetic and clinical aspects of foot-drop and gluteal necrosis.

Buttocks↗