Biomedical subjects

M Botero

Publications and source records attributed to M Botero.

3 recordsLinked to original sources

PubMed1988

Partial cognitive-dysmnesic seizures as a model for studying psychosis.

Nineteen patients were analyzed who exhibited cognitive-dysmnesic psychic partial seizures and structural damage shown by means of CT scans. It was observed that these seizures originated in the amygdala-hippocampal system, coinciding with the effects found when using electrical stimulation of the brain. An attempt is made to relate these findings to the present biochemical hypotheses of schizophrenia, the kindling effect and the genetico-maturational hypotheses. All these data seem to agree and point in the direction of the possible neurophysiological mechanisms of psychosis and of schizophrenia in particular.

Adolescent↗

PubMed1987

Palinopsia and visual allesthesia.

Two cases of palinopsia are reported. The first patient had palinopsia and visual allesthesia secondary to an occipital calcified cysticercus. Symptoms were more prominent during treatment for his parasitic infection. The second case was a patient with long standing vascular headaches associated for many years with episodes of visual persistence; he had a right occipital lobe infarct; he reported deformation of images, illusion of movement and macropsia in his left homonymous hemianoptic visual field. Different hypotheses for explaining palinopsia have been proposed. An analysis of our cases does not prove or disprove any of the current hypotheses. However, the current hypotheses do not necessarily contradict each other. Implications of the two cases reported are analyzed.

Adult↗

PubMedDate not supplied

Fulminant amebic colitis.

Amebiasis is the acute and chronic disease produced by Entamoeba histolytica, an entity which occurs in endemic fashion in many of the tropical and subtropical areas of the world, capable of affecting diverse organs of the body, especially the colon. Amebiasis has different clinical forms of presentation, varying from the asymptomatic carrier state to severe, although not frequent, fulminant or necrotizing colitis, characteristically associated with high morbidity and mortality. We hereby report a series of 50 adult patients with fulminating amebic colitis managed at our institution between January, 1971 and July, 1989, with a global mortality of 60%. Early diagnosis, treatment with effective antiamebic agents--specifically metronidazole--and opportune aggressive surgical intervention have resulted in better survival rates. We had no survivors prior to 1970; our current survival rate is still a dismal 40%, indicating the very severe nature of the disease.

Adolescent↗