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Biomedical subjects

M Boyle

Publications and source records attributed to M Boyle.

104 records · Page 6Linked to original sources

The role of social support systems in adolescent cancer amputees.

Amputation is often a component in the treatment of bone tumors such as osteogenic sarcoma, which is most prevalent in the adolescent age group. Adaptation to cancer and loss of a limb requires a significant multidimensional effort. To examine the role of social support systems, 27 adolescents who had undergone amputations for cancer were interviewed. Inquiries were made regarding patients' perceived social support providers and the impact of amputation upon their lives and independence. Parents, especially mothers, were perceived as realistic and most helpful at the time of surgery (80%), followed by professional hospital staff (59.3%), and siblings (59.3%). Friends of patients were less helpful, as many reported their friends felt sorry for them (65.4%), avoided them (33.3%), or drifted away (40%). Only 7.4% of the patients had a clear preference to be associated with other amputees. This study details other preferences and difficulties encountered by the adolescent amputees and the role of support systems in their adaptation to their disease and amputation.

Adolescent↗

Development of a cancer prevention-detection clinic.

Control of cancer through risk reduction and early detection has great potential. Roswell Park Memorial Institute's Prevention-Detection Center addresses a community need for health promotion, disease prevention, and cancer detection as well as providing opportunity for research on the efficacy of such a program. The Prevention-Detection Center offers a range of services including education, genetic counseling, risk assessment, counseling in smoking cessation and other means of risk reduction, and screening for cancer. It is also involved in evaluation of new technologies of cancer detection such as the ultrasonic examination of the breast. A community outreach program is aimed at attracting high-risk populations. In its first eighteen months of operation; the Prevention-Detection Center detected 24 confirmed cancers. The Center is used by approximately 60 persons each week. Interviews with persons using the clinic over a two-week period indicate that most are motivated to attend because a relative has had cancer or because of a belief in the importance of regular checkups. Client satisfaction with the clinic is high. Although many of the activities of the prevention-Detection Center have a research dimension, many of its activities and services are suited to the community ambulatory health care setting.

Cancer Care Facilities↗

Adolescent adjustment to amputation.

We investigated the psychological effects of amputation on adolescent patients by interviewing 27 persons who had a limb amputation because of cancer during their adolescence and compared them to data obtained from eight patients with amputations due to trauma at similar ages. In cancer patients, mobility-related activities and social matters including relations with peers and the opposite sex and self-consciousness were of paramount concern. All cancer patients considered themselves functionally independent and 67% had little or no concern for the future. While malignancy and amputation had a significant impact on the patients' lives, the vast majority had a positive view of life and 85% were found to have what we assessed as adequate overall adjustment. Individual variables examined included marital and child-bearing patterns, educational attainments, vocational attainments, perceived parental and peer support, adaptation to prosthesis, and variables relating to general outlook on life and psychological adjustment. Our results suggest that the patients who have had amputations due to malignancy differ from traumatic amputees in their adjustment to amputation, with cancer patients showing, in many instances, evidence of better adaptation to disability. This may in part be due to different backgrounds and social orientation of traumatic amputees. We found the majority of cancer amputees to adjust well to their circumstances and to report leading full and productive lives.

Adolescent↗

Effectiveness of a community program to promote early breast cancer detection.

There are no known means of preventing breast cancer, and efforts to control the disease must be directed toward early detection and improved treatment. To assist in achieving this, we developed a two-tier educational program aimed at educating women regarding breast cancer facts and the proper performance of breast self-examination (BSE). Educational efforts are first directed at nurses who are then encouraged to transmit this information to women and their partners in the community. The program combines a lecture and demonstration with more informal small group discussions that allow for individual demonstrations of the technique of BSE. Follow-up of both nurse and lay participants by means of telephone interviews has shown that women can be motivated to practice BSE, and be made aware of proper techniques.

Breast↗

Cholecystokinin and gallbladder contraction: effect of CCK infusion.

Cholecystokinin octapeptide (CCK-8) was infused intravenously in five normal subjects. Plasma levels of CCK-8 and infusion concentrations were measured by a specific radioimmunoassay and gallbladder volumes wee monitored using ultrasound. Calculated CCK-8 infusion rates were 16.4, 32.8, and 65.6 pmol.kg(-1) hr(-1). During infusion of the lowest dose plasma concentrations rose from 8 +/- S.E. 5 to 18 +/- 4 pmol.1(-1) equivalent to normal postprandial concentrations of CCK and were accompanied by a 76 +/- 7% reduction in gallbladder volume. Infusion at the two higher rates resulted in 87 +/- 3% and 88 +/- 3% reduction of initial gallbladder volumes returned to 73 +/- 26% of initial volumes within 30 minutes. These studies are consistent with the hypothesis that CCK is the main postprandial stimulus for gall-bladder contraction.

Cholecystokinin↗

The very low birthweight infant: impact on parents during the pre-school years.

This paper presents follow-up data on 75 families who had children born between 1970 and 1971 at birthweights under 1501 g (very low birthweight: VLBW) and a comparison group of 55 families who had children born at the same time but at birthweights over 2500 g. An interview done when the children were 3--5 yr old revealed that parents with a VLBW child gave a less favourable evaluation of their child in 2 of 7 areas considered: development and play. These differences of evaluation were caused by a subgroup of 22 VLBW children with neurological and/or intellectual defects. No evidence came forth to indicate that the experience of having a VLBW child had significant or continuing impact on the family. An absence of serious social problems such as child abuse or the child's failure to thrive were noted.

Adult↗

Mechanical ventilation of infants of less than 1,501 gm birth weight: Health, growth, and neurologic sequelae.

A two-year follow-up study of 73 low-birth-weight ( less than 1,501 gm) infants treated with positive pressure ventilation as neonates revealed the following: 24% incidence of lower respiratory tract infections during the first year; weight and height at two years averaging between tenth and twenty-fifth percentiles; major neurologic defects diagnosed in 14 boys (39%) and seven girls (18%) with one-year Bayley scores of less than 80. Major neurologic sequelae were closely associated with a neonatal history of seizures and intracranial hemorrhage and were more common in boys, survivors weighing more than 1,000 gm and following high-risk pregnancies.

Apnea↗

Drug overdosage.

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Humans↗

Objectives to direct the training of emergency medicine residents on off-service rotations: administration.

Administrative knowledge and skills are essential for the emergency physician. This is the 12th article in a continuing series of "off-service" goals and objectives. It outlines a mechanism for conveying important points of Emergency Medicine Administration to the EM III resident. The article includes materials describing the Administrative Content, Goals and Objectives, Key Contact System, and Contents of the EM Administrative briefcase. This information should assist faculty charged with the development or revision of the Administrative literature review and experiential block rotation in an emergency medicine residency.

Curriculum↗

Galactocele in a male infant: case report and review of literature.

An 11-month-old male developed painless enlargement of the left breast over 1 month. The lesion was mobile, fluctuant, and nontender. Surgical excision was performed and histological examination revealed a galactocele. A galactocele is a very rare cause of breast enlargement in male infants and children.

Breast Diseases↗