PubMed HealthSearch

Biomedical subjects

M Breda

Publications and source records attributed to M Breda.

At least 37 records · Page 2Linked to original sources

[Uncommon locations of celomic cysts: a possible cause of error in mediastinal radiology (author's transl)].

Five cases of uncommon locations of mediastinal celomic cysts are presented. All cases were surgically proved. The importance of these locations in the differential diagnosis of mediastinal masses is stressed. The evaluation of their inner structure by computerized tomography is, without doubt, the best progress in radiological diagnosis of the mediastinum. This method allows, atraumatically, to confirm or exclude the cystic nature of the lesion in one with its precise spatial localization.

Adult

Age-related changes of beta-endorphin and cholecystokinin in human and rat mononuclear cells.

Beta-endorphin (BE) and cholecystokinin (CCK) were measured in fresh PBMC isolated from human subjects and rats. The BE and CCK PBMC contents increased significantly with age both in human and rat models. Moreover, polyclonal stimulation induced a significant decrease of BE but not CCK contents in mononuclear cells from human aged subjects. The time course of changes in BE and CCK concentrations observed in fresh and cultured cells from subjects of different ages did not directly correlate to the time course of age-associated impairment of lectin-induced lymphocyte proliferative response and interleukin-2 synthesis. In fact, the lymphocyte functional defects were significantly observed only in the 71-99 year age group, whereas the neuropeptide changes were already evident in the 31-50 age group. Since BE has been shown to participate in the modulation of the immune system, the age-related modifications of PBMC BE could play a role in the immunodepression observed during aging.

Adult