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Biomedical subjects

M Brossard

Publications and source records attributed to M Brossard.

8 recordsLinked to original sources
PubMed1979

Passive transfer of resistance in rabbits infested with adult Ixodes ricinus L: humoral factors influence feeding and egg laying.

Parital immunity against the bites of female I. ricinus was transferred to normal rabbits by inoculating immune serum from resistant animals. Transferred humoral factors diminished the weight of the ticks' blood meal by 29% and increased the feeding period by about 1 day in comparison with ectoparasites engorged on controls. They provoked also the failure of egg laying by female I. ricinus. Only 55% of ticks fed on treated rabbits laid eggs (94% on controls). The immunological state of immune serum donors or recipients was studied and the IgG and homocytotropic specific anti-I. ricinus antibodies were identified. The immediate hypersensitivity of rabbits' skin was also controlled.

Animals↗
PubMed1977

Effects and duration of resistance acquired by rabbits on feeding and egg laying in Ixodes ricinus L.

Rabbits gradually developed a resistance against Ixodes ricinus ticks as a result of sequential experimental infestations. The resistance was characterized by an increase duration of feeding, by ticks engorging to a smaller extent and by reduced egg production. Once established, the immunity persisted for at least 9 months. Changes in the titre of circulating anti-I. ricinus antibodies was measured by indirect immunofluorescence.

Animals↗
PubMed1976

[Immunologic relations between cattle and ticks, specifically between cattle and Boophilus microplus].

In the present investigation, it has been demonstrated that cattle become resistant to ticks after several heavy infestations, particularly with B. microplus. During development of the infestations, antibodies against salivary glands of B. microplus were detected using 2 techniques: indirect immunofluorescence and immunoelectrophoresis. There is a positive causal relationship between antibody titer and resistance development. Two precipitating systems against B. microplus in infested cattle and 7 systems in immunized rabbits were studied. The systems 1 and 2 are similar in cattle and rabbits, but system 2 does not show any specificity, as it has been detected in cattle completely lacking tick infestations. Two one-day calves were treated with the antigen of B. microplus by injection of salivary glands and repeated infestations with a small number of larvae. They developed a pronounced resistance to the usual subsequent infestations by the ticks of the same species. Specific antibodies were found before the first usual infestation. This suggests that they might be responsible for resistance.

Animals↗
PubMed1975

[Contribution to the knowledge of Swiss piroplasmas].

The authors identify 3 species of Babesia, which parasitize cattle in Switzerland (Babesia major, B. divergens and B. hovis). They also confirm the presence of B. canis in a dog in the proximity of Geneva. Finally, for the first time in Switzerland, they point out the presence of non-identified Babesia in various rodents (Apodemus sylvaticus, A. flavicollis and Clethrionomys glareolus).

Animals↗