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Biomedical subjects

M Burrell

Publications and source records attributed to M Burrell.

47 records · Page 3Linked to original sources

Aperistalsis and esophagitis.

Aperistalsis of the esophagus was demonstrated in six patients with esophagitis. This was observed in reflux, caustic, and infectious esophagitis, and has occurred both as a transient phenomenon with no further sequelae, and as the initial manifestation of involvement in patients who subsequently suffered stricture. Based on biopsy and autopsy specimens in two cases, a possible mechanism of aperistalsis related to the damage to neurons in Auerbach's plexus is postulated. The presence of aperistalsis has been the first significant clue to esophageal inflammation in several cases.

Aged↗

Sequelae of stomach surgery.

Gastric surgery has undergone continuous evolution since the 19th century. At present it is a highly sophisticated technique which provides symptomatic relief for the vast majority of patients operated upon for peptic ulcer disease. Although the overall incidence of complications has decreased, a variety of complications continues to occur and radiological examination plays a critical role in their detection, evaluation, and management. Knowledge of the variations in surgical terminology and commonly used eponyms provides the basic framework for discussion. Familiarity with the radiological appearance of the normal postoperative stomach together with an understanding of its physiology are essential prerequisites to the recognition of possible complications. Operative techniques may result in a radiographic appearance which simulates disease. Conditions as diverse as bezoars, afferent and efferent loop problems, marginal ulceration, anastomotic leakage, prolapse, and intussuception may all be characterized by distinct and highly specific radiographic changes. Physiologic problems such as dumping and malabsorption may also reflect their presence by X-ray changes. The radiographic features in a large number of surgical complications are discussed and illustrated. The importance of the radiographic examination in the postsurgical stomach is emphasized.

Digestive System↗

Flexural pseudolesions of the duodenum.

A collection of barium simulating an ulcer, or a negative defect simulating a mass, frequently occurs at the junction of the first and second portions of the duodenum. This appearance may be related to several factors, including (a) distortion produced by flexion, (b) sphincter function, and (c) an extrinsic impression. Several such patients have had negative findings on endoscopy. The defect can be distinguished from a true lesion by its characteristic location and its variable appearance on different projections.

Adult↗

Esophageal aperistalsis secondary to metastatic invasion of the myenteric plexus.

A case of aperistalsis of the esophagus secondary to isolated invasion of the myenteric plexus of Auerbach by metastatic carcinoma is presented. The unique pattern of tumor involvement and the resultant aperistalsis supports the contention that involvement of the neurons in the deep myenteric plexus, either by inflammation or tumor, may be the key factor in producing aperistalsis. No similar cases were found in the literature.

Aged↗

Adenocarcinoma in biliary papillomatosis.

A patient with multicentric biliary papillomatosis associated with invasive adenocarcinoma of the bile duct is reported. This case documents the progression to malignancy of a lesion generally thought to be benign. It serves to alert clinicians to a rare but important cause of recurrent biliary obstruction. The literature on this entity is reviewed.

Adenocarcinoma↗

Hemobilia following percutaneous liver biopsy.

A patient underwent a routine percutaneous liver biopsy and subsequently developed gastrointestinal hemorrhage, biliary colic, and bilirubinuria suggesting the presence of hemobilia. After a negative arteriogram endoscopic cholangiography was used to confirm the diagnosis.

Adult↗

Clinical comparison of two contrast agents for oral cholecystography: radiologic efficacy and drug safety of iopanoic acid and iopronic acid.

Oral doses of either iopronic acid (4.5 g Oravue, Squibb) or iopanoic acid (3 g Telepaque, Winthrop) were given to 98 patients requiring cholecystography. Radiographs were taken 13 to 16 hours after treatment showed good to excellent gallbladder opacification in 44 percent of patients after the first dose of iopronic acid and in an additional 29 percent after a second dose. Similar opacification occurred in 42 percent of patients after the first dose of iopanoic acid and in 34 percent after a second dose. Drug-related abnormalities in blood and urine tests occurred about equally in both groups and one patient in each group exhibited a clinically adverse reaction (diarrhea). Thus, the performance (radiographic efficacy and drug safety) of the new contrast agent, iopronic acid, was similar to a widely used drug, iopanoic acid.

Administration, Oral↗