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M C Alfano

Publications and source records attributed to M C Alfano.

32 records · Page 2Linked to original sources
PubMed1976

Controversies, perspectives, and clinical implications of nutrition in periodontal disease.

Many controversies concerning the role of nutrition in periodontal disease and problems in the design and analysis of nutrition-periodontal disease studies have been reviewed. In addition, recent advances in the interactions of nutrition, host defense, and infection have been conceptually related to the pathogenesis of periodontal disease. Finally, nutritional factors relevant to the diagnosis and clinical management of patients with periodontal disease have been discussed. The concepts developed with respect to experimental design and the host defenses approach to periodontal disease, will hopefully serve to encourage definitive studies which may delineate a more precise role for nutrition in periodontal disease.

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PubMedDate not supplied

Localization of rate-limiting barrier to penetration of endotoxin through nonkeratinized oral mucosa in vitro.

The penetration of tritiated bacterial endotoxin through nonkeratinized oral mucosal epithelium was studied using an in vitro model system and radioautographic tracer techniques. The basement membrane region of the epithelium was the rate-limiting barrier to penetration, and this barrier effect was independent of the direction and duration of penetration as well as any clearance effects of the vasculature.

Animals↗