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Biomedical subjects

M C Barrio Andrés

Publications and source records attributed to M C Barrio Andrés.

4 recordsLinked to original sources

[Neonatal systemic candidiasis].

We analysed 7 cases of systemic candida sp. infection diagnosed between 1986 to 1989. Clinical presentation was of sepsis. Evolution was favorable in all, excepting two cases that died due to a candidiasic meningitis and a candidiasic aortic thrombosis, respectively. Almost all patients were treated with amphotericin B only. A newborn had signs of toxicity (thrombocytopenia). We emphasize the importance of a prompt diagnosis and treatment and the effectivity of amphotericin B for systemic candidiasis, besides of its rare toxicity in newborns.

Amphotericin B↗

[Spontaneous chylothorax: seven cases of prenatal diagnosis].

Authors present 7 cases of spontaneous congenital chylothorax, all of them diagnosed antepartum echographycally. Six of them needed cardiopulmonary resucitation but none presented fetal anoxia. Three cases had associated malformations. Treatment included thoracocenthesis, pleural drainage, assisted ventilation and appropriate nutrition. Pleural effusion lasted from 14 days to 6 months. Complications were: pneumothorax, metabolic acidosis and bacterial infections. Three patients died by respiratory failure. Pulmonary hypoplasia was present in two of them, and suspected in the third one. Survivors are free of symptoms.

Chylothorax↗

[Follow-up of children born to parents affected by the toxic oil syndrome].

Conditions at birth and evolution during the first year of life of a group of infants whose parents were affected by the Spanish Toxic Syndrome are presented. They are distributed in three groups: first those infants of high risk whose father or mother (or both) have consumed toxic oil; second children whose parents had consumed non-brandname oil not demonstrated to have been toxic and without signs of disease; and a third control group of normal newborns without previous medical history. From the present study, authors cannot affirm whether ingestion of toxic oil by pregnant women had influenced intrauterine growth or first year growth. Nonetheless, new studies are needed which clarify evolutionary aspects of these children.

Chemical and Drug Induced Liver Injury↗

[Congenital tuberculosis (author's transl)].

The present case report concerns a term infant, born of a mother with an undiagnosed tuberculosis, which was proved by inguinal lymph node biopsy to have numerous acid-fast bacilli; sequence of events supports the thesis that infant had acquired infection transplacentally. Literature is reviewed and diagnosis, prophylaxis, chemotherapy of this infrequent disease with a grave prognosis is commented, emphasizing success of chemotherapy in this infant.

Biopsy↗