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Biomedical subjects

M C Beachley

Publications and source records attributed to M C Beachley.

62 records · Page 4Linked to original sources

Transcatheter embolization of traumatic renal arteriovenous fistula.

An iatrogenic renal arteriovenous fistula was treated by transcatheter embolization with particles of absorbable gelatin sponge. Recurrent massive hematuria was successfully controlled. The procedure was easily accomplished with minimal loss of renal parenchyma. Surgery, which usually requires partial or total nephrectomy, was avoided.

Adult↗

Single isotope evaluation of pulmonary capillary protein leak (ARDS model) using computerized gamma scintigraphy.

Using a canine oleic acid model, a computerized gamma scintigraphic technique was evaluated to determine 1) ability to detect pulmonary capillary protein leak in a model temporally consistent with clinical adult respiratory distress syndrome (ARDS), 2) the possibility of providing a quantitative index of leak, and 3) the feasibility of closely spaced repeat evaluations. Study animals received oleic acid (controls, n = 10; 0.05 ml/kg, n = 10; 0.10 ml/kg, n = 12; 0.15 ml/kg, n = 6) 3 hours prior to a tracer dose of technetium-990m (99mTc) HSA. One animal in each dose group also received two repeat tracer injections spaced a minimum of 45 minutes apart. Digital images were obtained with a conventional gamma camera interfaced to a dedicated medical computer. Lung: heart ratio versus time curves were generated, and a slope index was calculated for each curve. Slope index values for all doses were significantly greater than control values (P(t) less than 0.0001). Each incremental dose increase was also significantly greater than the previous dose level. Oleic acid dose versus slope index fitted a linear regression model with r = 0.94. Repeat dosing produced index values with standard deviations less than the group sample standard deviations. We feel this technique may have application in the clinical study of pulmonary permeability edema.

Animals↗

Transcatheter embolization of angiodysplasia of the rectum. Report of a case.

A 51-year-old man with repeated and massive rectal bleeding was found to have a large angiodysplasia of the rectum. A superselective embolization of the distal part of the superior rectal artery with Ivalon controlled the rectal bleeding for 4 months. Lower gastrointestinal bleeding recurred and a recurrent lesion was re-embolized with Ivalon with excellent control of bleeding in a follow-up of 8 months. Embolization is an alternative to surgery for the treatment of rectal angiodysplasia and hopefully may result in a long-term cure.

Arteriovenous Malformations↗