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Biomedical subjects

M C Bossi

Publications and source records attributed to M C Bossi.

At least 19 recordsLinked to original sources
PubMed1992

[Therapy of subcutaneous cystic lymphangioma with ultrasound-guided puncture and alcoholization].

The sclerosing treatment of subcutaneous cystic lymphangioma was repeatedly attempted in the past, but only to be abandoned owing to the high frequency of inflammatory complications. The authors repropose this treatment method under US guidance and using 98% sterile ethanol. In 6 patients with subcutaneous cystic lymphangioma in only one location, a US-guided puncture was performed which was followed by complete drainage of the cystic cavity and alcoholization. US follow-up 2-18 months from treatment showed the complete disappearance of cystic cavities. The method was found to be simple, reliable, and to present no complications.

Adult↗
PubMed1991

Lissencephaly in two brothers detected by US. A "pseudo-liver" pattern.

We report on two cases of lissencephaly in two brothers studied by high frequency ultrasound and subsequently confirmed by CT and, in one case, by post-mortem study. In addition to well known sonographic and CT signs described in the literature, a typical structural change of the brain (named "pseudo-liver") was detected using high-frequency sonography.

Brain↗
PubMed1991

Toluene diisocyanate-induced asthma: clinical findings and bronchial responsiveness studies in 113 exposed subjects with work-related respiratory symptoms.

We report the clinical findings and the results of inhalation challenge with toluene diisocyanate (TDI) and methacholine in 113 subjects with a history of exposure to TDI and work-related respiratory symptoms. Only some of the subjects (40.7%) had isocyanate asthma, diagnosed by a positive TDI inhalation challenge. Most reactors had a dual (30.4%) or a late (41.3%) response. The interval between the last occupational exposure and the specific challenge was significantly shorter in reactors, and among this group the number of immediate reactions to TDI decreased progressively with an increasing interval. The reactors had a significantly higher proportion of positive responses to methacholine and a significantly lower mean PD15 FEV-1 (provocative dose of methacholine which provoke a 15% decrease in forced expiratory volume in 1 second) (reactors: 557 micrograms, SEM 92.3; nonreactors: 1346 micrograms, SEM 128, P less than .01). Methacholine challenge could not identify subjects with isocyanate asthma.

Adult↗
PubMed1985

Value of hepatobiliary scintigraphy and ultrasonography in the differential diagnosis of jaundice.

In order to compare the reliability of hepatobiliary scintigraphy using DISIDA (DHS) and ultrasonography (US) in the diagnosis of obstructive jaundice, 36 consecutive patients clinically suspected for obstruction were examined with both methods. Sixteen patients who were definitively shown to have obstruction, were all correctly detected with DHS; US was positive in 15 cases, revealing the cause of the obstruction in four cases. The site of obstruction was predicted in eight cases by DHS and in 11 cases by US. Associated gallbladder diseases were evaluated better by US than by DHS, but a perforation was only demonstrated clearly by DHS. In the 20 patients with nonobstructive disease the false positive results were found in one case using DHS and in two cases using US. In this series of patients DHS and US showed high sensitivity and specificity, which were further increased when the two techniques were combined.

Adult↗
PubMed1984

Ultrasound demonstration of changes in the normal portal venous system following a meal.

Eating might be expected to change vessel size within the portal venous system. The diameters of the portal and superior mesenteric veins were measured in thirteen normal individuals using B-mode ultrasound, initially fasting and then following a meal. We have shown a 50% increase in the diameter of both these vessels occurring between thirty minutes and one hour after a meal. The significance of this is discussed.

Adult↗
PubMed1984

Sonographically guided fine-needle aspiration biopsy of adrenal masses.

Percutaneous fine-needle aspiration biopsy of solid adrenal masses was performed under real-time sonographic guidance in 18 patients. Cellular material was aspirated in all cases. Cytologic examinations were correct in 11 metastatic deposits, three primary adrenal adenocarcinomas, and one pheochromocytoma. One subsequently proven primary adenocarcinoma was not diagnosed. In two cases of adenoma, normal adrenal cells were aspirated. Percutaneous aspiration of adrenal masses is recommended when the precise nature of the lesions is clinically required. The simplicity and speed of fine-needle aspiration biopsy under sonographic control and its high diagnostic accuracy and safety suggest its use as a routine procedure in the management of patients with adrenal masses well depicted by sonography.

Adenocarcinoma↗
PubMed1982

Detection of left atrial myxoma by Fourier phase image.

A case of left atrial myxoma shown on an equilibrium radionuclide ventriculography is presented. A peculiar abnormality of the Fourier phase image appears more reliable than the other findings previously revealed by first-pass or equilibrium studies. The findings were perfectly consistent with the gross anatomy of the tumour.

Adult↗
PubMed1981

[Platelet hyperaggregation premonitory of myocardial infarct? A clinical case report].

In a patient, treated with antiplatelet drugs because of two previous TIA episodes, an occasional control in apparent welfare, just 4 hours before the onset an IMA, showed a sudden considerable increase of spontaneous aggregation. Two weeks after the infarction all haematological findings, including aggregation, were back to normal. Platelet adhesiveness, evaluated for the first time, was nevertheless considerably increased. A treatment with an association of low doses of acenocoumarine and ASA was useful to take aggregation and adhesiveness firmly back to normal values that persist 22 month after the episode. Spontaneous platelet hyperadhesion, occasionally recorded a few hours before IMA, bears out the importance of the role played by platelets in vascular coronary accident. Authors suggest that it is therefore advisable to evaluate platelet adhesiveness too, regardless of the specific meaning of this test; it is worth investigating whether this monitoring should lead to some attempt whatsoever enabling to prevent recurrent crisis, adding to antiaggregant therapy, a management with anticoagulating drugs, administered with low dosage.

Anticoagulants↗
PubMed1981

Acute toluene poisoning. Electroneurophysiological and vestibular investigations.

Neurophysiological studies were carried out in six female workers of an electromechanical works after accidental exposure to toluene vapours. Electroencephalographic abnormalities and vestibular hyporeflexia were detected immediately after the accident. Six months later the EEG changes were still present, while vestibular findings were found to be markedly improved. Results of this study provide further evidence of the diagnostic value of vestibular investigations after toxic exposure to toluene.

Adult↗
PubMed1981

[Radiological diagnosis in 229 cases of breast fibroadenoma].

From 1976 to 1977, 705 patients with a fibroadenoma of the breast, histologically proven by biopsy, were observed at the Istituto Nazionale Tumori of Milan. In 229 cases, the clinical examination was followed by mammography or xeromammography; in 65/229 patients telethermography was also carried out. The aspects of fibroadenoma at x-ray examinations are described together with the difficulties to reach an exact diagnosis: the cases in which a false positive diagnosis of cancer was done are emphasized.

Adenofibroma↗
PubMed1980

[Platelet changes and occupational carbon disulfide poisoning. I. Variations of platelet adhesiveness].

Platelet adhesiveness was studied in 83 workers exposed to CS2 and 47 controls. Results show an increase of platelet adhesiveness statistically significant in workers in comparison with controls and in workers with high exposure vs. workers with mild exposure. Authors suggest the usefulness of platelet adhesiveness evaluation for prevention and early diagnosis of CS2 intoxication.

Blood Platelet Disorders↗
PubMedDate not supplied

[Role of high resolution color-Doppler US of the sentinel node in patients with stage I melanoma].

PURPOSE: The aims of the present work are to assess the diagnostic accuracy of high resolution color Doppler ultrasound (US) of the sentinel node (SN) in patients with cutaneous melanoma skin at stage I. The US findings of nodal involvement could spare the patient a surgical step (selective lymphaderectomy) allowing them to undergo radical lymphadenectomy directly. MATERIAL AND METHODS: From November 1998 to November 2000 94 patients (mean age 52.7 years) underwent lymphoscintigraphy in order to mark the SN site on their skin. An US scan (112 lymphatic basins) was performed within 24 hours with a 10-13 MHz electronic linear probe with color-power-Doppler (Esaote AU5 Idea Scanner, Genoa, Italy). The sonographic features we analysed were: shape (roundness index), hilum displacement, intranodal heterogenicity, eccentric cortical thickness, extranodal invasion, vessel irregularity. RESULTS: 26 nodes showed US findings consistent with malignant involvement, 86 were negative. All the nodes were surgically removed and controlled by histology. Sensitivity and specificity of US scanning were 89.4% and 90.3%, the positive and negative predictive values 65.3% and 97.6%, respectively. US correctly identified the involved SN in 15,1% cases, so that 17 patients could have avoided the selective lymphadenectomy CONCLUSION: Preoperative lymphoscintigraphy and high-resolution color-Doppler US scanning constitute a useful diagnostic tool in identifying the metastatic SN, with a low margin of error. False negatives were technically induced, even using the more recent scanners, by the low US probe resolution, unable to recognise metastatic microdeposits. The two most reliable parameters in identifying involved lymphnodes were the roundness index and the absence of hilar echo. The advent of technologically more advanced probes should allow better spatial resolution and assessment of lymph node vascularization, enabling diagnosis of metastasis measuring less than 2 mm in diameter.

Adolescent↗
PubMedDate not supplied

[Acute emphysematous cholecystitis].

A case of acute cholecystitis in a patient of 66 is reported. The aetiopathogenetic aspects are examined with particular regard to the microbiology of such forms, the particular radiological and anatomo-pathological findings and the medical and surgical implications, in the light of a review of the question.

Acute Disease↗