Biomedical subjects
Publications and source records attributed to M C Eybalin.
A simple and reliable technique was developed to measure split renal glomerular filtration (GFR) based solely on image processing of the standard 20-minute Tc-99m DTPA renogram. It requires neither syringe counting nor blood or urine sampling. Using three sequential blood samples in 36 patients, GFR values correlated well (r = 0.92) with in vitro GFR measurements.
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In view of the high rate of loosening of conventional cemented hip prostheses, cementless implants are gaining popularity in Europe and North America. Smooth-surfaced "press fit" prostheses are designed for autolocking in the femoral canal at the time of installation. Fifteen patients were prospectively followed by bone imaging with Tc-99m MDP at three-month intervals after cementless "press fit" hip arthroplasty to define the "normal" distribution of mechanical stress to the surrounding bone, as well as the incorporation of bone allografts used for reconstruction of resorption sites in cases of revision surgery.
Chondromyxoid fibroma is a relatively rare benign bone tumor whose histologic and radiologic patterns are well known. In this article, we describe a 16-year-old boy with such a tumor in his left tibia. Scintigraphically, this tumor is represented by a "doughnut sign". This aspect, though not pathognomonic, has been reported sporadically in a few diseases: osteoporosis circumscripta cranii, angioblastic meningioma, cranial coccidioidomycosis, and aseptic necrosis of frontal bone. Because of their sites, it is easy to reject these diagnoses in our patient. The most pertinent differential diagnosis with regard to the clinical, radiological, and scintigraphic aspects in the patient is that of a giant cell tumor.
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