PubMed Health⌕ Search

Biomedical subjects

M C Kayser-Gatchalian

Publications and source records attributed to M C Kayser-Gatchalian.

9 recordsLinked to original sources

Sural nerve conduction in mild polyneuropathy.

The motor conduction velocity of the lateral popliteal and tibial nerves as well as the maximal sensory conduction velocity of the sural nerve were measured in 187 patients with signs and symptoms suggestive of mild or early polyneuropathy. The maximal sural conduction velocity gave a high diagnostic yield compared to the motor conduction velocity of the nerves in the legs. In the neuropathies in which the predominant pathological abnormality is known to be axonal degeneration, the maximal sural conduction velocity was often showed in patients with normal motor conduction velocities. The amplitude of the sensory potential did not prove helpful in individual cases because it was often within the normal range.

Adolescent↗

The prognostic value of EEG in ischaemic cerebral insults.

In a prospective study the authors analysed the EEG and clinical parameters in 79 patients with an acute ischaemic cerebral insult in the territory of the internal corotid or the middle cerebral artery. The findings within 48 h after the onset of the vascular accident, on the 10th and the 22nd days were evaluated. The data show that the initial focal and background changes correlate significantly with the severity of the initial clinical findings provided the EEG is registered within the first days (in this investigation within the first 48 h) of the illness. The time of registration of the EEG is of major importance in determining correlations between the neurological deficits and the EEG changes. Although a significant correlation exists between the initial focal changes and the state of consciousness and severity of motor impairment of the first day, the focal EEG changes have no prognostic value regarding the outcome of the ischaemic insult. The background changes in the initial EEG give reliable information about the return of function and the clinical courese of an ischaemic insult in its acute stage, i.e., death, worsening, no change from onset or improvement. Diffuse slowing of the EEG corresponds to the impairment of consciousness, which is a manifestation of the degree and extent of brain damage caused by the ischaemia.

Adult↗

Peripheral neuropathy with vitamin B12 deficiency.

Seven patients with neuropathy associated with vitamin B12 deficiency are reported. Four of them had other signs of malabsorption aside from the abnormal Schilling test. The neuropathy was diagnosed on the basis of the whole clinical picture and the neurophysiological findings. The pathogenesis of the peripheral nerve disease is discussed in the light of the evidence in the literature.

Adult↗

Thrombosis and intracranial tumors.

334 necropsy reports of intracranial neoplasm from an autopsy material over 13 years were reviewed to study the relationship of intracranial tumors to vascular thrombosis. The incidence of venous thrombosis in intracranial tumors was found to be 27.5% while that of a control group without malignancies taken at random from the autopsy material was 17%. The difference gives a statistical significance of P less than or equal to 0.05. The parameters of sex, surgical intervention, the malignancy and the histological type of the tumor apparently dod not affect thrombus formation to a statistically significant degree. There is increased thrombosis frequency with increasing age. The presence of hemiparesis or hemiparalysis does not affect the incidence of thrombosis. However, it determines to a great degree the lateralization of the thrombus.

Adolescent↗