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Biomedical subjects

M C Level

Publications and source records attributed to M C Level.

13 recordsLinked to original sources
PubMed1989

[Pulmonary and muscular localization of Wegener's granulomatosis. Apropos of a case].

The authors report their observations on a patient presenting with Wegener's granulomatosis with initially isolated pulmonary involvement. Following treatment with a combination of steroid therapy and immunosuppressives muscular involvement developed with specific histological changes. The disease was only controlled by substituting at the same dose prednisone for the methylsulphobenzoate of prednisolone which was prescribed initially; this suggests in equivalent doses the superiority of one product over the other was achieved by a different pharmacodynamic behaviour.

Aged↗
PubMed1980

[Bacterial counts in sputum. The value and interpretation in lower respiratory tract infections (author's transl)].

A convenient and effective microtechnic of bacteria numeration in sputum has been used and its results are presented, considering the accompanying clinical data. One has therefore been able to appreciate the signification of the number and prevalance of bacteria isolated in lower respiratory tract infections: 1) The concentration of 10(7) bacteria/ml is a useful critical value, but it does not mean either virulence or lower limit of pathogenicity. 2) The importance of the predominance of a bacterial strain is an essential parameter in quantitative analysis. 3) The interpretation of the bacteriological results can only be made after thoroughly examining the cytology, the clinical infection symptoms, the anamnestic data, and considering the possibility of an antibiotic therapy preceding the test.

Bacteria↗
PubMed1979

[Mucoepidermoid tumors in the bronchi. About three cases (author's transl)].

The little frequent mucoepidermoid tumors in the bronchi can be distinguished by their histological characteristics associating epidermoid and mucilage-like cells identified through alcian blue and PAS colour agents. Although these tumors are normally considered as "benign", some of them may have a capacity to develop in very malign way. We enclose three new findings which all developped unfavorably in a short period.

Bronchial Neoplasms↗
PubMedDate not supplied

[Pulmonary fibrosis during a case of dermatomyositis (author's transl)].

The authors describe the case of a pulmonary interstitial fibrosis, the discovery of which preceeded the skin and muscular manifestations of dermatomyositis which was confirmed by a muscular biopsy. The aetiopathogenesis of the pulmonary disorder is not well known, nevertheless an immunological mechanism demonstrated in the experimental myositis is suggested but has yet to be proved.

Adrenal Cortex Hormones↗
PubMedDate not supplied

[A critical study of immuno-enzymatic reactions coupled with the precipitation tests on cellulose acetate membranes].

Precipitating tests carried out on cellulose acetate membrane can be increased by treating the immune complexes with enzyme linked anti-immunoglobulin antibodies. From our trials in parastic diseases (Amoebiasis, schistosomiasis, fasciolasis, filariasis, hydatidosis, trichinosis) and mycosis (Aspergillosis, Candidiasis), it seems that the immuno-enzymatic labelling of the "active" precipitating reactions should only be taken in consideration. We must insit on the importance of ELIEDA (enzyme-linked-immuno-electrodiffusion-assay) and ELIDEPA (enzyme-linked-immuno-double-electro-phoresis-assay). Both of these analytical assays are particularly sensitive. The sequence of appearance of the multiple precipitating systems of the complex parasitic mosaic can easily be watched. The different classes of immunoglobulins and their kinetics are determined by the use of monospecific antibodies linked to different enzymes which give a polychromic specific staining.

Amebiasis↗