Circadian rhythms: basis for screening for fever.
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Biomedical subjects
Publications and source records attributed to M C Long.
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The recovery of coliform organisms on Gelman and Millipore membranes was analyzed by using both a model I (which assumes no error in the x variable) and model II (which allows errors in both the variables) regression analysis. The two models afford estimates of the slope which agree within their 95% confidence limits. Using equations derived in this paper, the model II confidence limits on the intercept are obtained. This range does not include the model I intercept limits, thereby demonstrating the differences between results from an incorrect (model I) and correct (model II) approach. In addition, fecal coliform show no differences in response to the two membranes, whereas total coliform exhibit higher recoveries on Gelman membranes.
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A previous investigation by our laboratory linked cellulose acetate degradation with adverse health effects in hemodialysis patients. To establish the accumulation of degradation products with time, a Monte Carlo model of degradation kinetics was developed. The model tracks changes in a population of molecules representative of the dialyzer membrane during the degradation process. The degradation calculation is a two step process: First, the model uses a random number to select an individual polymer molecule out of the population, and then a second random number is used to identify a site on the selected molecule for the degradation reaction to occur. After the reaction calculation, the resulting degraded molecules are redistributed into the population. The course of the reaction is determined by recalculating the molecular weight averages in the changing population as the calculations proceed. The model was validated using gel permeation chromatography molecular weight results and total acetyl content measurements on dialyzers stored up to 13.3 years after manufacture. It was found that the degradation reactions can be accurately modeled as random events and that the chain scissions and deacetylation events occur at constant rates. The shelf life of these devices was estimated using the model predictions and animal test results.
A clinical performance examination was developed for basic baccalaureate nursing students and used to validate the clinical skills of registered nurses entering a baccalaureate degree program. With few exceptions, RNs returning to school demonstrated clinical competence in the secondary care area as measured by this examination. Therefore, another means of validating RN clinical skills was developed based on the evaluation criteria used for the clinical performance examination. Using employer and colleague validation, students individually documented competence in the area of practice. There was a decrease in student stress, an increase in self-esteem, conservation of the time and energy of students and faculty, and more effective use of program resources.
In an effort to increase knowledge and attitudes toward promoting health rather than treating disease, faculty in one school developed an elective wellness course open to all university students. The authors discuss how students learned concepts of wellness and developed individualized plans to improve their own health status.
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