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Biomedical subjects

M C Perez

Publications and source records attributed to M C Perez.

24 records · Page 2Linked to original sources
PubMed1982

Balo's concentric sclerosis--a case report.

This is a report of Balo's concentric sclerosis in a 23-year-old Filipino male, who presented behavioral abnormalities, gait disturbance, double incontinence and generalized paratonia with the entire course of a six-month duration. A review of literature on this rare form of demyelinating disease is discussed.

Adult↗
PubMed1981

Stable remissions in myasthenia gravis.

Forty-two myasthenic patients received a total of 7.6 to 130 gm of cyclophosphamide over 2 to 37 months; 33 received prednisone concomitantly. Twenty-five (60%) are presently asympatomatic. Seventy-four percent improved after 1 month of therapy. Fifty-eight percent of those treated for a year, 86% of those treated for 2 years, and 100% of those treated for 32 months were asymptomatic. Based on our definition of remission (asymptomatic for at least 6 months without medication), 12 of the 16 patients (75%) followed for at least 18 months were in remission. Cyclophosphamide may have more specific therapeutic effects than other immunosuppressive drugs used to treat myasthenia.

Adolescent↗
PubMedDate not supplied

Scintigraphic quantitation of splenic function in SLE: correlation with IgM levels in serum.

The relationship between quantitative splenic uptake of sulfur colloid and immunoglobulin M level in serum was studied in 15 patients with systemic lupus erythematosus (SLE). Splenic function correlated positively with IgM level (r = 0.58, p = 0.02) and inversely with antibody titre to n-DNA (r = -0.74, p = 0.003), and was reduced (p greater than 0.001) in patients with depressed IgM levels. IgM level in serum may be a useful correlate of splenic phagocytic function in SLE patients.

Adult↗