Confluent and reticulated papillomatosis: response to isotretinoin.
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Biomedical subjects
Publications and source records attributed to M C Ray.
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We present the case of a patient who experienced a silent colonic perforation while being treated for pemphigus vulgaris with prednisone and azathioprine. Dermatologists are experienced in the management of pemphigus vulgaris with prednisone. We report a well-recognized but rarely reported adverse effect of this standard therapy for pemphigus vulgaris.
The atypical or environmental mycobacterial organisms constitute a large group of potential agents in the pathogenesis of cutaneous infection. The most commonly encountered mycobacterial infection after contact with water is Mycobacterium marinum. We report an unusual case of cutaneous mycobacterial infection caused by a newly described opportunistic mycobacteria, M. avium-intracellulare scrofulaceum intermediate. This case emphasizes the difficulty in distinguishing among the species M. avium-intracellulare, M. scrofulaceum, and M. gordonae.
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A mother and daughter with lichen sclerosus et atrophicus (LSA) are described. Both had lesions restricted to their lower legs. Both patients were positive for HLA-B40, which has been associated with LSA. Sex steroid hormones showed no decrease in dihydrotestosterone, free testosterone, or androstenedione levels in the daughter as was demonstrated in a previous study of this disease, but did show some decrease in androstenedione in the mother. This article provides further evidence for a possible familial predisposition for LSA.