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Biomedical subjects

M C Snella

Publications and source records attributed to M C Snella.

23 records · Page 2Linked to original sources
PubMed1975

Bacterial contamination of organic dusts: effects on pulmonary cell reactions.

The influence of water extracts from different organic dusts on the number of free lung cells was studied in short-term exposure experiments. A large increase in the number of leukocytes was found 24 hours after exposure to extracts from cotton and hay. The number of macrophages was not affected. The increase was greater when the dusts were incubated at 37 C and 100% relative humidity prior to the preparation of the extract. This procedure caused an increase in the number of bacteria. When different bacterial species were studied endotoxin-producing strains were found to cause the largest effect.

Animal Feed↗
PubMed1975

Pulmonary cell response patterns after exposure to airborne bacteria.

The free lung cells obtained with a lavage technique were studied in guinea-pigs exposed to an aerosol of E.coli, K. pneumoniae or B.subtilis. An increase in the number of polymorphonuclear leucocytes was found 5-48 hours after exposure to E.coli and B.subtilis. The clearance of a mixture of viable and radioactively labelled E.coli was studied in animals with a naturally present or artificially induced high leucocyte level in the lungs. It was found that animals with the higher leucocyte number cleared the inhaled bacteria faster.

Aerosols↗
PubMedDate not supplied

[Endotoxins: a neglected environmental factor].

The effects of bacterial endotoxins are well known form an experimental and clinical point of view. Their presence in the environment in general and their possible role for the development of clinical symptoms at low exposure levels has been less studied. Experimental and epidemiological evidence for such effects are reviewed with reference to particular environments where this exposure might be present.

Acetobacter↗