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M C Tierney

Publications and source records attributed to M C Tierney.

25 records · Page 2Linked to original sources
PubMed1989

WAIS-R test-retest reliability in a normal elderly sample.

We examined the 1-year test-retest reliability of WAIS-R Verbal, Performance, and Full-Scale IQs in a sample of 101 older normal individuals (mean age = 67.1). The respective Pearson rs were .86, .85, and .90. The median retest reliability coefficient for the WAIS-R subtests was .71. The test-retest reliability for the Verbal-Performance Discrepancy was .69. These data indicate that IQ scores are reliable in older normal individuals for this retest interval, but less confidence can be placed in the reliability of subtest scores and the Verbal-Performance Discrepancy.

Aged↗
PubMed1989

Dementia diagnosis.

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Alzheimer Disease↗
PubMed1988

The NINCDS-ADRDA Work Group criteria for the clinical diagnosis of probable Alzheimer's disease: a clinicopathologic study of 57 cases.

Neuropathologic confirmation is required to validate the NINCDS-ADRDA Work Group criteria for the clinical diagnosis of Alzheimer's disease (AD). Neuropathologic inclusion and exclusion criteria for AD, however, are not uniform. The purpose of this investigation was to examine the confirmation rate for the Work Group criteria against differing neuropathologic criteria for AD. The sample consisted of 57 cases, 22 of which had received a clinical diagnosis of AD. Nine neuropathologic criteria for AD were applied in a blind fashion to each of the 57 cases. Our results indicated that, depending on the neuropathologic criteria applied, the clinicopathologic agreement ranged from 64% to 86%. These findings demonstrate the need for universally accepted neuropathologic and clinical criteria for AD.

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PubMed1987

Psychometric differentiation of dementia. Replication and extension of the findings of Storandt and coworkers.

In a previous investigation by Storandt and coworkers, a brief battery of four neuropsychological tests was found to accurately distinguish a sample of patients with senile dementia of the Alzheimer type (SDAT) from normal elderly persons. The present study examined the value of these tests in the distinction between SDAT and dementias of other etiologies. Our results replicated those of Storandt and coworkers in that these tests did distinguish normal persons from patients with both SDAT and other dementias. These tests, however, did not accurately differentiate among the dementias. These results indicate that assessment batteries utilizing additional procedures to supplement cognitive testing are indicated to more accurately discriminate among the dementias.

Aged↗
PubMed1986

The differential diagnosis of Alzheimer's disease: conceptual and methodological issues.

The study of Alzheimer's disease is hampered by insufficient knowledge of its cause. It can best be described as a syndrome whose clinical and pathological features, and their associations over time, need to be more carefully examined. Issues which impede our understanding of this syndrome include the lack of: a singular "gold standard" for its identification; longitudinal studies with appropriate comparison groups and neuropathological follow-up; and standardized multifaceted clinical assessment procedures. Our awareness of the significance of these issues has led us to undertake a large-scale prospective, longitudinal investigation of 399 dementing and normal individuals at Sunnybrook Medical Centre. As a result of problems identified, it is proposed that research efforts across various Canadian centres be coordinated to best utilize available resources and expertise.

Alzheimer Disease↗
PubMed1975

Egocentrism and conformity in childhood.

Fifty-two grade one children were tested on measures of communicative egocentrism and conformity. Contrary to Hartup's suggestion that egocentric children are not as likely to conform as less egocentric children, the results indicated the reverse. A three stage hierarchy of decentration skills was postulated to explain the conformity data. During the first stage, children center solely on their own judgments during social influence situations. Second, upon entering school, increased peer interaction may force the child to center on the opinions of others. Finally, the child begins to decenter when he simultaneously considers his own and others' judgments.

Age Factors↗