[Clinicoechocardiographic evaluation of tricuspid insufficiency. A comparative study with angiographic and preoperative findings].
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Biomedical subjects
Publications and source records attributed to M Córdoba.
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In order to correlate functional and biochemical parameters, frozen bovine sperm samples presenting diverse motility were studied. Specimens collected from four bulls (A, B, C and D) were graded according to motile spermatozoa percentage and vigour, regarding the sample from bull A as highest motility, those from bulls B and C of intermediate motility and that from bull D of low motility. In order to evaluate lipid peroxidation enhanced by the addition of sodium ascorbate and ferrous sulphate, thiobarbituric acid reactive substances (TBARS) were measured. Values were 0.34 +/- 0.18 and 4.95 +/- 0.31 nmol TBARS/10(8) spermatozoa for samples A and D, respectively. Superoxide dismutase (SOD) activity was 144 +/- 16.48 and 44 +/- 4.0 IU/10(10) spermatozoa for A and D, respectively, while intermediate values were recorded for samples B and C. The capability to undergo acrosome reaction induced by calcium ionophore A23187 was significantly lower for sample D, but differences were negligible for the remaining three samples inter se. Motile spermatozoa percentage correlated closely both with SOD activity (r = 0.92) and with TBARS production (r = -0.80), but not with acrosome reacted percentage (r = 0.65). From correlation data, it would be inferred that motility is not entirely indicative of sperm quality.
The long-term evolution of 36 patients surviving the phase of hospitalization after a postero-inferior infarction with extension to the right ventricle was studied. Patients included 7 women and 29 men with a mean age of 55 years. Follow-up time averaged 39 months (range: 4 to 78 months). The evolution of acute phase was analyzed and correlated with mortality, complications and long-term evolution of functional capacity. Mortality at the end of follow-up period was 5.5%. Five patients developed another myocardial infarctions (16%). No patient manifested right heart failure; in one case tricuspid regurgitation was evident. The majority of the patients (55.5%) were in functional class I of the NYHA, while 36.6% were in class II and 8.3% in class III. We conclude that long-term mortality of those patients with right ventricular infarction is not greater than that of other patients with myocardial infarction, and that the great majority have a favorable evolution in regard of functional capacity. Impared function is generally due to left ventricular failure secondary to the severity and extension of coronary lesions. The subgroup of patients with severe right ventricular dysfunction during the acute phase of the infarction did not have a worse long-term prognosis.
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Coronary angioplasty has shown its efficacy in "high-risk" patients for surgical treatment (severe left ventricular failure, serious pulmonary or systemic disease). We studied a subgroup with multivessel coronary heart disease treated with coronary angioplasty because they were no candidates for surgery due to unsuitable coronary anatomy. Revascularization rate was determined in each patient as revascularization percentage obtained, compared with all the technically suitable lesions for coronary angioplasty. Ten patients (mean age 63 years) were studied, eight of them had unstable angina. Overall, 44 lesions were considered technically suitable for angioplasty and thirty-five could be dilated, technical success rate was 88% (31/35 lesions) and revascularization rate was 71% (31/44 lesions). Primary success rate was achieved in nine patients. Clinical follow-up varied from two to thirteen months (mean 7.8 months); eight patients have remained asymptomatic (class I of NYHA), another patient had stable angina and the other one had sudden death six months after the procedure. In conclusion, we demonstrated a high success rate in a short and long term with coronary angioplasty in a subgroup of patients with multivascular coronary heart disease that had been rejected for surgery due to unsuitable coronary anatomy.
The present work is part of a presentation given at the Scientific Meeting of the Association for Surgical Nutrition and Metabolism, during the XX National Congress for Surgery (Madrid, November 1994). The authors, prior to presenting their experiences, define and high light the importance of the phenomenon of "Bacterial Translocation" (BT). Afterwards, and based on several experimental studies performed by them, they attempt to answer two questions: 1) Is the term BT correct? 2) Is BT a physiological or a pathological state? Finally they review the relationship which exists between bacterial translocation and nutrition, both from a causative point of view as from the prevention and therapy of the same.