Role of breast feeding in paralytic poliomyelitis.
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Biomedical subjects
Publications and source records attributed to M Cafiero.
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In the first part of the paper the Authors give an up-to-date analysis of our current knowledge of magnesium metabolism, its relation with other electrolytes (namely sodium, potassium, calcium) and clinical symptoms due to its deficiency. The Authors then focus their attention on the relations between magnesium and cardiovascular pathologies and underline the role which magnesium deficiency may play in the onset of various forms of coronary artery disease: preinfarction angina, myocardial infarction, threatening ventricular arrhythmia and sudden death.
A population-based cross-sectional study of antenatal and perinatal care was performed in Campania, a region of southern Italy. One thousand three hundred women who had given birth in 1982 were interviewed. The number of antenatal visits was very low, less than 1% of the mothers having attended more than three times during pregnancy. The women at high obstetric risk did not attend more than those at low risk and certain aspects of their antenatal care were unsatisfactory. The place of birth was similar for high risk and low risk mothers, with 40% delivering in small private facilities (with few neonatal resuscitation facilities and often with inadequate infant transport services). The labour was induced or accelerated in 60% of the mothers. The organisation of perinatal care did not take into account many of the needs of the mothers such as presence of a relative at delivery, ambulation during labour, early relationship with the newborn, rooming-in, or encouragement to breastfeed.
One hundred obstetricians and 50 paediatricians engaged in public antenatal and perinatal care in southern Italy were interviewed about the provision of care in their facilities: 93% of the obstetricians judged the coverage of the target population to be insufficient and 53% of them considered the use of the risk approach to be unsatisfactory in public clinics. For example, no initiative was taken by 60% of public clinics when a woman at high risk failed to attend a booked antenatal visit. Bed rest during labour was prescribed by 72% of the obstetricians, a supporting relative was admitted to only 18% of the births and routine episiotomy was performed in 77% of primigravidae. Only 56% of the paediatricians interviewed allowed early contact between mother and baby. In public hospitals, 80% of paediatricians were present in the delivery room for the births. Screening for congenital hypothyroidism and phenylketonuria was executed in only 37% of the public hospitals. Newborn transport system adequate to national standards was available in only 33% of the hospitals. Antenatal and perinatal care need to be rapidly improved to meet population needs in southern Italy.
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We report the genomic organization of 20 human class I homeoboxes and the predicted primary sequence of the encoded homeodomains. These homeoboxes are clustered in four complex HOX loci on chromosomes 2, 7, 12, and 17. The homeoboxes of one HOX locus can be aligned to the homeoboxes of the other HOX loci so that corresponding homeodomains in all loci can share the maximal peptide sequence identity. This correspondence of individual homeoboxes in different chromosomal loci suggests the hypothesis of large-scale duplications of a single complex locus. The existence of an ancestral complex locus might have predated the divergence of vertebrates and invertebrates.
The main purpose of this study was to make an objective assessment of emotional stability as a selection criterion in 14 heart transplant candidates (13 M, 1 F, 45.5 +/- 6.6 years). A psychometric study was conducted using Cognitive Behavioral Assessment (CBA 2.0 Primary-Scale Battery) and the Beck Depression Inventory. The main results of this study were the identification of: a) emotionally unstable patients (42%) who did not respond to the above mentioned selection criterion; b) stable psychological traits such as hostility, aloofness, extroversion as described in type A Behavior Pattern and c) the presence of secondary alexitimic responses suggesting a protective denial of the meaning of the disease. The psychometric method used seems useful in the selection of heart transplant candidates, however, a follow-up can better define the range of emotional stability.
Results with a new anti-angina molecule (nifedipine: Adalat) in the long-term management of 28 patients with ischaemic heart disease are presented. The effectiveness of the drug was judged outstanding on the strength of its reduction of angina outstanding on the strength of its reduction of angina crises and consumption of NTG beads. Non side-effects were noted.
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