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Biomedical subjects

M Caforio

Publications and source records attributed to M Caforio.

8 recordsLinked to original sources
PubMed1997

[Perioperative complications in traditional surgery of the rectum].

The authors report their experience of 136 operations for rectal neoplasms, on all of 652 colo-rectal neoplasms, treated from January 1987 to May 1994. In detail the perianastomotic complications have been tested after "traditional" rectal operations: Anterior Resection (RA), Abdomino-perineal amputation (AAP) and Hartmann's procedure. A series of 24 AAP (18%), 81 RA (60%) and 7 Hartmann's procedure have been considered; conversely 18 final and palliative colostomies (13%) and 7 trans-anal operations haven't been taken in to account. Perioperative mortality was comparatively reasonable: 2.7%. No patient died after AAP. The most common complication proved to be anastomotic leak (17.3%), after RA; otherwise the rate of further complications was very moderate. It is feasible to avoid anastomotic leaks, by carrying out a temporary colostomy.

Aged↗
PubMed1997

Four years experience of primary intra-arterial chemotherapy (PIAC) for locally advanced and recurrent breast cancer.

AIMS: To find a means of achieving operability very quickly without the additional discomfort of prolonging systemic chemotherapy. To improve the patient's quality of life by obtaining quick tumor reduction and decreasing systemic toxicity. MATERIALS AND METHODS: From January 1991 to January 1995, 13 patients with locally advanced breast cancer (LABC) and 8 patients with recurrent breast cancer (RBC), were treated by transfemoral Seldinger technique, with the catheter tip placed into the subclavian artery at the basis of the internal mammary artery. The patients received 5-fluorouracil (5FU) 1000 mg, epirubicin (EPI) 30 mg/m2, mitomycin (MMC) 7 mg/m2 over an infusion for 30 minutes. The cycle was repeated every two weeks for three times. RESULTS: The overall response rate was 62%. Stage IIIb and RBC patients had a response rate of 100% and 25% respectively. In respondent patients a measurable response was seen after the first cycle. Ten patients were radically operated. After a media follow-up of 21 months, the overall survival is 52% at 48 months (68% at 48 months and 65% at 34 months for stage IIIb and RBC patients respectively). CONCLUSIONS: PIAC is feasible and effective. In LABC patients it reaches 100% of response rate. Systemic toxicity was absent and the local one was mild. The interval between the starting of PIAC and operation is short. There was an optimal compliance of the patients.

Adult↗
PubMed1980

[Doppler ultrasound assessment of lower limbs arterial occlusive disease (author's transl)].

The Authors evaluate the Doppler ultrasonic detection in the assessment of lower limbs arterial occlusive disease, particularly concerning the haemodynamic pattern of those patients undergoing a surgical treatment. The research is accomplished on a group consisting in hundred not selected patients, all subjected to aortography. A comparative study was undertaken between angiographic findings and ankle sistolic pressure measurement together with flow velocity profile. Reduction of ankle sistolic pressure and appearance of flow velocity profile changes, resulted highly correlated with clinical stage and angiographic alterations. The Authors consider therefore the Doppler ultrasound assessment as being able to give, together with the always necessary angiographic study, more accurate informations either on the run-off and the haemodynamic consequences of a stenosis, or on the overall evaluation of multisegmental lesions.

Angiography↗
PubMed1979

[Doppler observations in migraine patients (author's transl)].

The Authors have subjected 14 migraine patients to Doppler ultrasonic technique. Examinations have been performed on both common carotid arteries, either in headache phase or in pain-free periods. Results in each case suggest variable hemodynamic patterns during migraine attacks. Possible pathogenic mechanisms are discussed.

Adolescent↗
PubMedDate not supplied

[Splenic artero-venous fistula and portal hypertension. A case report with review of the literature].

Splenic artero-venous fistula (SAVF) is a rare but potentially curable cause of pre-hepatic portal hypertension. About 100 cases have been reported in the world medical literature. The Authors report a case of 46-year-old man with a splenic artery aneurysm and a large SAVF treated by surgical resection of splenic vessels and splenectomy. The literature about SAVF is reviewed to recognize etiology, anatomical location, main symptoms at presentation, diagnostic findings and management of this rare syndrome.

Arteriovenous Fistula↗