Biomedical subjects
Publications and source records attributed to M Calandriello.
We found that three cases of giant papillary conjunctivitis responded well to local specific desensitization therapy and transplantation of the conjunctiva with saphenous vein tissue.
In the gingival crevicular fluid (GCF) of control and chronic adult periodontitis (CAP) patients there is a spontaneous release of O2- radicals from polymorphonuclear leukocytes (PMN). The addition of the exogenous stimuli phorbol myristate acetate (PMA) decreased the O2-. formation in control GCF, while in CAP patients produced a marked enhancement of O2-. generation. The circulating PMN of control subjects did not show a spontaneous O2-. formation, differently from CAP patients. On the contrary, a similar O2-. production was measured when the circulating PMN were stimulated with PMA. Moreover, the antioxidant activity measured in 10 microliters of cell free gingival supernatant (GS) of control and CAP patients had the same values by inhibiting 12.6% and 18.9% respectively of the O2- formation supported by a xanthine/xanthine oxidase system. Probably, the protective or destructive effect of PMN in GCF of CAP patients depends on the variations of the rate of O2- formation in respect to the intrinsic antioxidant property of GS.
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Defects of the bone margin requiring ostectomy and osteoplasty include hyperostotic processes, formations which, while recalling palatine and mandibular tori, have their own nosological slot. Hyperostosis is characterized by thickening of the cervical margin and is linked by a narrow isthmus to the underlying bone plane; it occurs with greatest frequency in the vestibular region. The personal case, in a man of 52, presented two sausage-shaped protuberances located apically at the alveolar margin in the two left arches. Their removal presented no problem of surgical technique as the hyperostosis had no close links with the underlying bone planes. Histological examination of the fragments showed that the hyperostotic tissue consisted of fascicular bone with an intima vascular component. Two years after the operation, the patient presents no signs of relapse and would appear to be completely cured.
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Localisations, evolutions and complications of oral cavity hemangiomas are discussed in the first part of the work. The Authors enumerate the principal clinical uses of cryosurgery showing its utility in hemangiomas therapy. The Authors report about principal cryo-units, their utilisation and working, examining literature on the argument. Description of five cases of hemangiomas treated by cryosurgery complete the work.
After a short account of principal precancerous oral lesions the Authors refer about cryosurgery principles and its effects on tissues. After an excursion on the literature about the problem, the Authors refer their experiences on seven cases of oral dyskeratosis treated by cryosurgery.
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