Biomedical subjects
M Calvin
Publications and source records attributed to M Calvin.
Tertiary and quaternary structure of tobacco mosaic virus and protein. I. Effect of pH on fluorescence and 2-p-toluidinylnaphthalene-6-sulfonate binding.
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Tertiary and quaternary structure of tobacco mosaic virus and protein. II. Emission, excitation, polarization and position of 2-p-toluidinylnaphthalene-6-sulfonate binding.
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Amino acid-nucleotide interactions on an insoluble solid support. I. A simple model of the amino acid acceptor terminus of a tRNA.
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Effect of dimethylbenzyldesmethylrifampicin (DMB) on chemically induced mammary tumours in rats.
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On the active site topography of isoleucyl transfer ribonucleic acid synthetase of Escherichia coli B.
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Induced nucleophilic substitution in benzo(a)pyrene.
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Chemical volatilization as a technique for the detection of extraterrestrial biopolymers and possible metabolic products.
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Synthesis of some rifamycin derivatives as inhibitors of an RNA-instructed DNA polymerase function.
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Detergent effects on a reverse transcriptase activity and on inhibition by rifamycin derivatives.
A reverse transcriptase activity, extracted from virus-transformed cells, is activated by very low concentrations of nonionic detergents. These same detergents also significantly reduce the effectiveness of certain rifamycin derivatives as inhibitors of the polymerase activity when the detergents are present at micelle-forming concentrations.
Isoleucyl transfer ribonucleic acid synthetase of Escherichia coli B. A rapid kinetic investigation of the L-isoleucine-activating reaction.
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An investigation of specific interactions of deoxyribonucleic acid and lysine-rich (F1) histone preparations.
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Synergistic effect of rifamycin derivatives and amphotericin B on viral transformation of a murine cell line.
One of the most potent inhibitors of RNA-dependent DNA polymerase activity so far described (rifazacyclo-16) was not correspondingly as active in focus inhibition. This discrepancy was thought to be due to the inability of the drug to penetrate the cell membrane. It has been found that a very low level of amphotericin B allows this drug, as well as the previously described 2',6'-dimethyl-N(4')benzyl-N(4')-[desmethyl] rifampicin, to exhibit a very high capability to inhibit focus formation. Since these two drugs are highly lipophilie, their activity may be expected to be dependent upon any lipophilic components in the medium, such as serum or detergents. The use of amphotericin B as well as serum in tissue cultures is common, and could account for some of the variability in focus inhibition reported in the literature.
Inhibition of MSV viral function by rifampicin derivatives.
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Carcinogenesis: chemical and otherwise.
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Spectroscopic investigation of the inhibitory effect of fatty acids on photosynthetic systems.
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2-p-Toluidinylnaphthalene-6-sulfonate, a fluorescent reporter group for L-isoleucyl-tRNA synthetase.
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Mechanism of action of p-hydroxybenzoate hydroxylase from Pseudomonas putida. 3. The enzyme-substrate complex.
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