PubMed Health⌕ Search

Biomedical subjects

M Campo

Publications and source records attributed to M Campo.

27 records · Page 2Linked to original sources
PubMed1980

[Action of levamisole on lymphocytic reactivity in naso-laryngeal carcinoma].

It was confirmed that the mitogenic reactivity and rosette-forming cells capacity of T and B lymphocytes were depressed in nose-pharyngeal tumor bearing patients. Using levamisole treatment, the response of T cells was increased till almost the normal value. B cells response was normal or slightly increased after levamisole treatment. Our experiments suggests that the levamisole is capable to induce an increased response of the immune system when compared to untreated tumor bearing patients.

B-Lymphocytes↗
PubMedDate not supplied

Molecular identification of streptomycin monoresistant Mycobacterium tuberculosis related to multidrug-resistant W strain.

A distinct branch of the Mycobacterium tuberculosis W phylogenetic lineage (W14 group) has been identified and characterized by various genotyping techniques. The W14 group comprises three strain variants: W14, W23, and W26, which accounted for 26 clinical isolates from the New York City metropolitan area. The W14 group shares a unique IS6110 hybridizing banding motif as well as distinct polymorphic GC-rich repetitive sequence and variable number tandem repeat patterns. All W14 group members have high levels of streptomycin resistance. When the streptomycin resistance rpsL target gene was sequenced, all members of this strain family had an identical mutation in codon 43. Patients infected with the W14 group were primarily of non- Hispanic black origin (77%); all were US-born. Including HIV positivity, 84% of the patients had at least one known risk factor for tuberculosis.

Adult↗
PubMedDate not supplied

[Stability of theophylline in mono- and multi-layer parenteral nutrition bags].

The addition of drugs to parenteral nutrition (PN) presents a high risk of physical and chemical incompatibilities. In certain patients with water restriction or limited vein access, however, it may be necessary to add medicines to PN. Although there are numerous studies into the stability of aminophylline in PN, all of them refer to periods of less than 2 days. The purpose of the present study is to determine the stability of anhydrous theophylline over 24 hours at room temperature in 24 hours parenteral nutrition and over five days (four days stored in refrigerator and 24 hours at room temperature). In addition, to assess whether its degradation is affected by the use of single-layer or multi-layer bags. The composition of PN corresponds to a standard 1,800 Kcal diet at our hospital with a concentration of 0.164 mg/ml of anhydrous theophylline. No statistically significant differences were obtained in any of the cases studied, thus demonstrating the stability of theophylline under our study conditions both after 24 hours at room temperature and after four days of storage in the refrigerator followed by 24 hours at room temperature. Nor were differences found between storing the drug in single-layer and multi-layer bags.

Drug Packaging↗
PubMedDate not supplied

[Disk diffusion method for fluconazole susceptibility testing of Candida spp. isolates].

In order to standardize and evaluate a disk diffusion method with visual reading to detect in vitro fluconazole susceptibility of yeast, 1193 clinical isolates were tested. These included 584 Candida albicans, 196 Candida parapsilosis, 200 Candida tropicalis, 113 Candida glabrata, 50 Candida krusei and 50 Candida spp. and other opportunistic yeasts. The disks were manufactured in the INEI-ANLIS "Dr. Carlos G. Malbrán. The disk diffusion method results were compared to MIC results obtained by the reference CLSI M27-A2 broth microdilution method modified by EUCAST. The interpretative breakpoints for in vitro susceptibility testing of fluconazole were established at: zone diameter > or =16 mm for MIC < or =8 microg/ml (susceptible isolates), between 9 and 15 mm for MIC = 16-32 microg/ml (susceptible dose-dependent isolates), and < or =8 mm for MIC > or =64 microg/ml (resistant isolates). Overall agreement between the two methods was 94.7%, with 0.2% very major errors, and 0.3% major errors. Inter - and intralaboratory agreement was good. The disk diffusion method for drug susceptibility testing of Candida spp. isolates is inexpensive, reliable and reproducible. However, when the inhibition zone diameter is < or =15 mm, it is advisable to test the isolate by the reference microdilution method.

Antifungal Agents↗