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Biomedical subjects

M Cashman

Publications and source records attributed to M Cashman.

8 recordsLinked to original sources

Ultrasound imaging in the preoperative estimation of the size of tracheostomy tube required in specialised operations in children.

BACKGROUND: Some children are dependent on a tracheostomy for many years. As they grow, larger tracheostomy tubes may be required. Although tables of sizes of tracheas exist for different age groups, they are estimations of normal and may not be accurate for atypical cases. Chest radiographs and computed tomograms (CT) have been used experimentally to estimate tracheal sizes, but are not in regular use. METHOD: High-resolution diagnostic ultrasound imaging was used to estimate the internal and external transverse tracheal diameter, and the depth of the trachea from the skin surface. This allowed selection of the correct standard pattern tracheostomy tube, or the construction of a custom-made tube preoperatively. RESULTS: Four children with various abnormalities who were being considered for replacement tracheostomies were scanned. In one, diagnostic ultrasound confirmed that a new larger fenestrated tube could be placed, which subsequently improved vocalisation and respiration. In the other three, the scan showed there was no space to allow a larger tube to be placed. The standard tables were not suitable for any of these patients. CONCLUSION: High-resolution ultrasound has a role in the non-invasive measurement of the size of the tube needed for specialised operations in children.

Abnormalities, Multiple↗

Cholecystokinin-induced protection against gastric injury is independent of endogenous somatostatin.

Cholecystokinin (CCK) prevents macroscopic injury to the stomach from luminal irritants by an unknown mechanism. The present study was undertaken in conscious rats to ascertain what role gastric mucosal blood flow, sensory neurons, and endogenous somatostatin play in CCK-induced gastric protection. Subcutaneous administration of CCK (10-100 micrograms/kg) significantly reduced macroscopic injury to the acid-secreting portion of the stomach caused by 1 ml of orally administered acidified ethanol (150 mM HCl, 50% ethanol) and augmented gastric mucosal blood flow (fluorescent microspheres) in a dose-dependent fashion. However, although the protective response to CCK (100 micrograms/kg) was still present at 2 h, the blood flow response had returned to baseline by 45 min. Ablation of capsaicin-sensitive afferent neurons with capsaicin (125 mg/kg sc) did not negate CCK-induced protection. Pretreatment with exogenous somatostatin (1 pmol-1 nmol/kg sc) failed to prevent the damaging effects of acidified ethanol to gastric mucosa. Immunoneutralization of endogenous somatostatin with somatostatin monoclonal antibody (2 mg ip) did not reverse the protective actions of CCK. Thus the data suggest that although CCK may prepare the gastric mucosa to withstand a damaging insult by augmenting gastric mucosal blood flow, its protective mechanism is independent of intact sensory neurons and endogenous somatostatin.

Animals↗

Duplex ultrasonography of recurrent varicose veins.

Varicose veins are a common clinical finding with a high recurrence rate following treatment with either surgery or sclerotherapy. Patterns of incompetence in 100 limbs with recurrent varicose veins were determined using duplex ultrasonography. Saphenofemoral or recurrent groin tributary incompetence was present in 44 limbs, an incompetent long saphenous remnant in 20, saphenopopliteal incompetence in 28, perforator incompetence in 35 and deep venous incompetence in 22. No significant incompetence was detected in 15 limbs. The findings suggest an important role for deep venous incompetence in recurrent veins and show that a re-exploration of the groin is unnecessary in over half of limbs with recurrent veins.

Humans↗

Identifying hearing loss and hearing handicap among chronic care elderly people.

This research assessed the appropriateness of the 1989 ASHA Draft Guidelines for the Identification of Hearing Impairment/Handicap in Adult/Elderly Persons for an institutionalized population. We tested 104 elderly chronic care residents using a conventional audiometer, an AudioScope3TM screener, and the Hearing Handicap Inventory for the Elderly. Results showed that this population is capable of performing these tests. Screening should be done at 2,000 Hz only. However, the prevalence of hearing loss is so high (69%) that we recommend conventional testing of all institutionalized elderly where feasible.

Aged↗

Duplex ultrasound mapping of sites of deep to superficial incompetence in primary varicose veins.

Most patients undergoing treatment for primary varicose veins have only a clinical assessment or examination with a continuous wave Doppler. In this study duplex ultrasound was used to determine the site of deep to superficial reflux in 137 limbs of 96 patients presenting with primary varicose veins. The incidence of saphenopopliteal (22%) and perforator (28%) incompetence was higher than that in previous studies based on clinical examination. Only five limbs had deep venous incompetence at the popliteal level and three of these limbs had lipodermatosclerosis or ulceration. The saphenopopliteal junction was either absent or more than 10 cm from the knee joint in 13% of limbs. The information obtained from duplex scanning of patients with primary varicose veins facilitates surgical management and may lead to a lower recurrence rate.

Femoral Vein↗

Effect of recent hearing aid improvements on management of the hearing impaired.

Recent developments in hearing aid technology and earmold acoustics have improved the outlook for the hearing impaired. Advances involving the electric microphone, integrated circuit, and earmold/hearing aid coupling system have affected such features as compression amplification, filtering, and frequency characteristics of the amplified signal at the eardrum. The resulting changes in hearing aid fitting approaches are described, including factors which are considered in such fittings as in-the-ear, binaural, CROS and BICROS, with examples of difficult cases. Hearing aids are then discussed in the context of a broader rehabilitation strategy.

Acoustics↗

Schools out.

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Female↗