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Biomedical subjects

M Cassou

Publications and source records attributed to M Cassou.

14 recordsLinked to original sources
PubMed1985

[Hypophosphatasia in adults. Apropos of 2 cases].

Two very dissimilar cases of hypophosphatemia in the adult patient are described by the authors. The first case was symptomatic since childhood, with typical clinical and radiologic findings (fissures, diaphyseal bone spurs, bony deformities), whereas the second case was minimally symptomatic (loss of teeth and back pain). Articular chondrocalcinosis was observed in both cases, as was a decrease in alkaline phosphatase and the increased urinary excretion of phosphoethanolamine. Histological examination demonstrated an increase in osteoid. Review of the literature revealed 40 cases of this inborn error of metabolism seen in adulthood, enabling a detailed description of the characteristics of this polymorphic condition.

Adult↗
PubMed1983

[Unusual muscular manifestations in a case of Horton's disease].

The authors report the case of a 66-year-old woman with temporal arteritis. The unusual muscular involvement consists in proximal muscle wasting, electromyographic changes and increased muscle enzyme levels. The improvement of these objective manifestations under steroid therapy allows to include them in the systemic spectrum of temporal anteritis. Attention is drawn to the infrequency of such objective manifestations published in the literature on temporal arteritis or polymyalgia rheumatica.

Aged↗
PubMed1977

[Radioimmunologic determination of plasma parathormone in hypercalcemia caused by cancer with osseous metastases].

The plasma parathormone was measured by radioimmunological determination in 23 cases of cancer with bone metastases, 8 of mammary origin. In 11 cases the plasma parathormone (iPTH) was less than 4 ng/ml (lower normal limit), as might be expected in view of the hypercalcemia. In 12 cases the iPTH was higher than 4 ng/ml, in 8 of these higher than 8 ng/ml (upper normal limit). These results are suggestive of the role of a substance analogous to parathormone in the genesis of the hypercalcaemia and peritumoral bone resorption of bone metastases of solid tumors.

Adult↗
PubMedDate not supplied

[Intravertebral gaseous lucency. Apropos of 7 new cases].

The authors report a personal series of 7 new cases with an appearance of intra-vertebral gaseous lucency, which was described by Maldague et al. [16] in 1978. They found the majority of the features of the disease as described in the 44 cases reported in the literature: advanced age, female predominance, predilection for the thoraco-lumbar junction, constancy of diffuse bony demineralization and the possibility of metabolic disturbances. Case no 2 suggests the hypothesis of a pathology induced by bismuth salts and cases no 3 and 4 raise the question of the benign nature of this appearance. Finally, the authors show that this image is not so much rare as mis-diagnosed. 4 of the 7 cases were found during a retrospective study of 140 case-files.

Adult↗