Biomedical subjects
Publications and source records attributed to M Caulier.
The authors report an 80-year-old woman who was evaluated for pain in her left leg and ankle. Sixteen years earlier, she had received a diagnosis of monostotic Paget's disease at the same site, based on roentgenographic changes. The lesion was very unusual, with tumor-like lysis of the affected area and fusion of the tibia, fibula, and talus.
We describe 2 cases of a lupus syndrome induced by sulfasalazine in rheumatoid arthritis. All symptoms resolved and antihistone antibodies disappeared when sulfasalazine was discontinued. In one patient, perinuclear antineutrophil cytoplasmic antibodies with specificity for myeloperoxidase were found critically increased just before the occurrence of vasculitis.
OBJECTIVES: To determine whether the Epstein-Barr virus is present in synovial membranes and subcutaneous nodules of patients with rheumatoid arthritis. METHODS: A sensitive in situ hybridisation technique was applied to tissue sections of 11 synovial membranes and five rheumatoid nodules. RESULTS: Cells carrying the Epstein-Barr virus were not detected using EBER and BHLF1 oligonucleotides in the tissue samples investigated here. CONCLUSIONS: Although it has been suggested that the Epstein-Barr virus could play a part in the aetiology of rheumatoid arthritis, it was not detected in synovial membranes and subcutaneous lesions in this study.
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Visceral Larva migrans is a human infection by the larvae of dog ascarids or, more rarely, ascarids of other animal species. It is endemic in France. Two cases which respectively manifested as acute oligoarthritis and inflammatory myalgia with increased muscle enzyme levels are reported. Manifestations of the minor forms of this infestation are reviewed.
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Two typical cases of Parsonage-Turner syndrome with reflex sympathetic dystrophy syndrome and adhesive capsulitis of the shoulder are reported. The rarity of this combination is discussed.
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The authors report three different types of cranial bone lesions due to a meningioma of the convexity. This rare tumour is most often benign, with variable radiological appearances. The diagnosis is often suggested by tangential views of the cranial vault and CT scan but meningioma remains a histological diagnosis, notably in its primary intra-osseous form without actual meningeal involvement. The prognosis is good and the risk purely local, by vascular or cerebral compression. Treatment is surgical, sometimes complicated by recurrence.
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Massive osteolysis of Gorham is a clinical, radiographic, and histologic entity characterized by histologically benign vascular proliferation involving bone associated with extensive osteolysis. We present CT and MRI findings of the disease and serial radiography following the progressing bone destruction.
A case of reflex sympathetic dystrophy involving the hip with a pathologic fracture of the femoral neck in a pregnant patient is reported. The low incidence of this condition is underlined and its characteristics are reviewed. The role of increased fragility related to pregnancy is discussed.
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