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Biomedical subjects

M Ceccarelli

Publications and source records attributed to M Ceccarelli.

88 records · Page 5Linked to original sources
PubMedDate not supplied

[The prevalence of celiac disease in children with short stature in the absence of other symptomatology].

Using an enzyme-linked immunosorbent assay (ELISA), the authors studied the sera of 116 patients with short stature of undetermined cause and no gastrointestinal symptoms, for the levels of IgG and IgA antigliadin antibodies (AGA). AGA of IgG and IgA isotypes were positive in 8 patients (group 1); only AGA IgG were positive in 7 patients (group 2). Both groups with positive AGA had subsequent duodenal biopsy that showed a villous atrophy in all children in group 1 and in two in group 2. These patients showed a significant acceleration in height velocity after the introduction of a gluten-free diet.

Adolescent↗
PubMedDate not supplied

[Clinical aspects of celiac disease. Comparison of 2 periods: before and after the introduction of antigliadin antibody determination in clinical practice].

The clinical aspects of coeliac disease before and after anti-gliadin antibodies (AGA) assessment in clinical practice, referring to personal experience (107 cases in the period 1976-1988) are described. AGA determination has executed by two different ELISA methods. The diagnosis of coeliac disease in the period 1976-1986 has been made according to ESPGAN criteria, while in the last two years following the recent SIP advice. After 1987 with the introduction of AGA assay, the number of diagnosis/year of coeliac disease has increased three times in respect of the period 1976-1986. We have observed a more marked increase of the late beginning forms (from 2.8 to 10 diagnosis/year) in respect of the early beginning ones (from 3.7 to 7.5 diagnosis/year) and of the atypical forms (from 0.7 to 9 diagnosis/year) in respect of the typical ones (from 5.8 to 8.5 diagnosis/year). According to these data we think that prevalence of coeliac disease in our country is probably underestimated. AGA determination is at time most effective mean to make a screening of coeliac disease in the population. According to us the largest employment of this method in the next years could take a most exact estimate of the coeliac disease prevalence in our country.

Adolescent↗
PubMedDate not supplied

[Serum bile acids in the newborn: our experience].

The study of bile acids in the newborn permits to the AA. to point out that the beginning of the feeding does not influence the "physiologic cholestasis" of the first days of life. Neonatal cholestasis is the expression of the immaturity of bile acids synthesis and hepatic and intestinal carriage, which is not correlated with the maternal conditions. Furthermore, the AA. discuss about the analogy between cholestasis and "physiologic hyperbilirubinemia", from which it differs for the longer time. In fact, the maturation of the enterohepatic circle occurs very slowly under possible dietetic factors influences.

Adult↗
PubMedDate not supplied

[Fecal chymotrypsin in the evaluation of exocrine pancreatic function].

In this study the Authors examine the usefulness in determining Fecal Chymotrypsin (FC) as a screening test for pancreatic exocrine insufficiency. The FC was measured in 503 children (337 control subjects and 166 with various intestinal and hepatobiliary diseases). The results demonstrate that FC is usefull as a screening test for pancreatic insufficiency. However, in certain cases, this should be supplemented by the more discriminant analysis of function provided by duodenal studies.

Adolescent↗
PubMedDate not supplied

[Intolerance to cow's milk proteins: cases contribution].

The authors report their own case-report about cow's milk protein intolerance observed in the last seven years in the gastroenterology-department of Pediatric Clinic in Pisa. They underline the symptomatologic polymorphism of the illness and, analysing the laboratory data, point out the absence of absolute diagnostic assurance tests. For this reason they conclude that at the present state the diagnosis of certainty is overall committed to the resolution of the symptomatology after exclusion-diet and following clinic relapse after milk load.

Child, Preschool↗
PubMedDate not supplied

[Yersinia enterocolitica septicemia in a girl with thalassemia major].

The Authors report the case of a child affected with Thalassemia Major who has presented a Yersinia Enterocolitica infection in a septicemial form. They point out that the clinical overture and its swift evolution with heart involvement make the diagnosis and the treatment difficult and, at the same time, urgent. They talk about the conditions which promote the septicaemia in this hemopathy.

Adolescent↗
PubMedDate not supplied

[2 cases of cardial achalasia in childhood. Diagnostic aspects and therapeutic possibilities].

The authors present two case-studies of achalasia in infancy and the emphasize the rarity of the illness in this stage of life. They point out that a correct diagnosis requires a meticulous anamnesis which should be followed by a radiological, endoscopic and manometric study. The authors discuss their therapeutical experience with Nifedipine and they suggest that it should be used while waiting for surgery.

Child↗
PubMedDate not supplied

[Celiac disease and cystic fibrosis: casual association?].

The authors describe a case of association cystic fibrosis coeliac disease, which they have observed. The frequency of this association in the general population is of 1:2,000,000. M.A. presents little growth in terms of height and weight and intestinal alterations (an abundance of fatty and mucous stool). The initial diagnosis was that of coeliac disease. After two months of diet without gluten one observed an increase in weight, but o result for the intestinal disturbances. The positive result revealed from the sweat-test and the study of genomic mutation (delta F508) showed the diagnosis of cystic fibrosis associated with coeliac disease. The specific treatment of both syndromes resolved intestinal alterations and caused the diminution of the acute bronchitis frequent during the first and the second infancy.

Celiac Disease↗
PubMedDate not supplied

[Williams-Beuren syndrome and celiac disease].

The authors describe a case of Williams syndrome-Coeliac Disease that they have observed at the age of three years and 10/12. There are few reports in the literature. We focus on the variability of clinical and biochemical aspects of Williams Disease and the necessity for an adequate gastroenterologic follow-up (anti-gliadine antibody and anti-endomisium antibody) in these patients with little growth in terms of weight and height and intestinal alterations present in superior measure in companion with the reported standards for the same syndrome.

Antibodies↗
PubMedDate not supplied

[Acute osteoarthritis in the newborn and infants].

The Authors report two cases of acute osteomyelitis, in a newborn and in an infant. Bone and joint sepsis in the first years of life is rare. The metaphases of long bones are the most common sites of hematogenous osteomyelitis. The hip and the knee are especially at risk. The patients were treated with pharmacologic and orthopedic therapy. The Authors describe the clinical features, radiographic changes, the diagnosis and management of this disease.

Acute Disease↗
PubMedDate not supplied

[Reiter's syndrome. Apropos a pediatric case].

The authors report the case of a 13-year-old girl affected with urethritis, conjunctivitis, and oligoarticular arthritis. These symptoms represent the classical triad of Fiessinger-Leroy-Reiter's syndrome. The research for HIV was negative and the antigen HLA B27 was absent. The young patients has been treated by FANS and tetracycline. The authors reviewed the literature and analyses the epidemiology-cal, etiological and clinical problems of this disease.

Adolescent↗