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Biomedical subjects

M Cernák

Publications and source records attributed to M Cernák.

6 recordsLinked to original sources
PubMed2003

[Is it possible to accurately measure intraocular pressure after refractive surgery?].

OBJECTIVE: To evaluate how the change of thickness or curving of the cornea after refraction operations (PRK or LASIK) influences the intraocular pressure (IOP) during assessment with a noncontact tonometer. PLACE OF INVESTIGATION: Ophthalmological Clinic SPAM and Ophthalmological ambulance EXCIMER. MATERIAL AND METHODS: With regard to the performed refraction operation the patients were divided into two groups. The first group comprised 87 patients where PRK was performed to correct myopia. The mean myopia in this group was -5.27 D +/- 2.32. The second group comprised 62 patients where LASIK surgery was performed to correct myopia. The mean myopia in this group was -10.18 +/- 4.36. IOP was assessed by means of a noncontact tonometer before and 6 months after surgery. RESULTS: In the first group a mean reduction of IOP by 4.8 +/- 2.1 mm Hg occurred. The central thickness of the cornea declined on average by 55.69 +/- 28.9 micros and the curving of the cornea diminished on average by 3.72 D +/- 1.76 D. In the second group of patients the IOP declined on average by 7.97 +/- 2.04 mm Hg. The central thickness of the cornea diminished by 78.75 microns +/- 42.26 and the curving of the cornea by 4.65 D +/- 2.07. In both groups a significant correlation was found between the reduction of IOP and the central thickness and curving of the cornea. CONCLUSION: Diminution of the thickness of the central cornea and diminution of the curving lead to lower values of the IOP. There is a direct correlation between thinning of the cornea and the decline of IOP.

Adolescent↗
PubMed2002

[Treatment of severe caustic injuries of the anterior segment of the eye with limbal stem cell transplantation, penetrating keratoplasty and amnionic membrane transplantation].

The concept of limbal stem cells (LSC) opened new possibilities for the treatment of severe caustic damage of the anterior segment. These possibilities include transplantation of LSC, perforating keratoplasty, possibly transplantation of the amniotic membrane. In three patients with severe caustic damage of the anterior segment of the eye the authors implemented transplantation of LSC, perforating keratoplasty and in one patient also transplantation of the amniotic membrane. Where only one eye was damaged LSC for transplantation were obtained from the sound eye (autotransplantation, in case of damage of both eyes LSC were obtained in one case from a close relative in the second case from a cadaverous eye from a corneal bank (Allotransplantation). In the patient with autotransplantation of LSC, perforating keratoplasty and transplantation of the amniotic membrane the result was very good. The corneal disc remained clear 1.5 years after operation, the conjunctival sac was free from synbleropharons and vision improved from movement of the hand to 0.5. In the two patients with allotransplantation of LCS and perforating keratoplasty, LCS did not become incorporated despite immunosuppressive treatment and the corneal disc became turbid. Restored activity of LCS in severe caustic damage of the anterior segment opened new therapeutic opportunities.

Amnion↗
PubMed2002

[Evaluation of the quality of a donor cornea before transplantation].

UNLABELLED: Transplantation of the cornea is often the only possible treatment of many ophthalmological diseases and injuries. The quality of the donor cornea determines in a major way the success of transplantation and therefore the demands on its quality must be high. OBJECTIVE: Assess how the vitality of the endothelium changes in relation to the time which elapsed since the donor's death after storage of the cornea in the medium (death/preservation time, DPT). If the vitality of the endothelium is poor, the oedema of the cornea persists at room temperature. METHODS: The endothelium of the donor cornea was examined before transplantation under a specular microscope Bio Optics (USA). According to DPT the corneae were divided into three groups: 1st group--22 corneae where DPT is shorter than 5 hours 2nd group--33 corneae where DPT is 6-10 hours 3rd group--46 corneae where DPT was longer than 10 hours. RESULTS: In the first group the corneae got rid of the oedema after 20 minutes at room temperature and endothelial cells could be observed in detail. In the second group the corneae got rid of the oedema after 20 minutes but there were rare oedematous sites where the endothelial function was not adequate. In the third group even after long time at room temperature the cornea did not get rid of the oedema, and on examination it was very difficult to find a group of endothelial cells for evaluation. CONCLUSION: Corneae from group 1 have a totally vital endothelium, in the second group there are sites on the cornea where the vitality of the endothelium is already impaired, in the third group the vitality of the entire endothelium is impaired. For transplantation corneae with a DPT shorter than 10 hours are suitable. With a DPT longer than 10 hours they are less suitable or unsuitable for transplantation.

Cadaver↗
PubMed1999

[Bimanual irrigation/aspiration].

Bimanual irrigation/aspiration is a safe method for the removal of lenticular mass from the eye and can be used in some complicated cases. As it is a perfectly closed system, oscillation of the posterior capsule does not occur and this prevents prolapse of the vitreous body. If the pupil is narrow, the margin of the pupil can be shifted by means of the irrigation cannula and thus suction of the lenticular mass up to the equator is made possible. In subluxed lenses by gently pushing back the lenticular capsule its adherence to the aspiration cannula is prevented. It is relatively easy to clean the anterior lenticular capsule from epithelial cells by bimanual I/A.

Cataract Extraction↗
PubMed1999

[Tonic pupil].

Authors evaluated the group of 21 patients (22 eyes) with pupillotonia. There were 2 postraumatic pupillotonias, 1 bilateral pupillotonia with systematic polyneuropathy in alcoholism, 6 Adie's pupillotonias and 9 postviral pupillotonias. In 4 one-sided pupillotonias there were finded no traumatic, viral or neurological cause. 2 patients (2 eyes) with traumatic cause, 2 patients with Adie's pupillotonia and 9 patients with viral cause had indicated the marked subjective difficulties in the eyes with pupillotonia--blurred vision, cephalea. After local application of Pilocarpin in 0.05%-0.1% concentration, these patients were indicating the marked improvement of their subjective troubles of the eyes.

Adolescent↗