Biomedical subjects

M Chesler

Publications and source records attributed to M Chesler.

57 records · Page 4Linked to original sources

PubMed1985

Alternative professional roles in health care delivery: leadership patterns in self-help groups.

The increasing professionalization of health care delivery systems, improved client awareness, funding cutbacks, and an emphasis on voluntarism have led recipients of health services to turn increasingly to self-help groups. This article examines the leadership and organizational pattern of such groups, using a study of 43 self-help groups from around the U.S. whose members are parents of children with cancer. Three leadership patterns emerged: groups were independent and parent-led, were led by professionals, or had a shared leadership of parents and professionals. Data indicate that the professionally led groups were the smallest, least formal, and had the narrowest range of activities. The groups with shared leadership had the greatest longevity, tended most often to retain as members parents of deceased children. The authors conclude that such coalitions of clients and professionals are vital for ensuring proper service delivery at a time when health care systems will likely remain bureaucratic and public resources for professional care are being reduced.

Adult↗

PubMed1981

Mechanical properties of a slow muscle in the cockroach.

The mechanical properties of the metacoxal muscle, 177d, in the cockroach, Periplaneta americana, was investigated. The muscle exhibited a mean resting tension of 2.6 +/- 1.3g SD. Neurally evoked tension summed with the resting tension and the relaxation phase of the evoked tension varied from less than 1 s to several minutes. This residual tension varied not only in duration but also in amplitude. Stimulation of inhibitory axons increased the rate of relaxation and thereby abolished the residual tension. However, inhibitory stimulation never reduced the resting tension. Stimulation of the main leg nerve at several times the threshold of the inhibitory axons could evoke residual tension. Recording of synaptic potentials from the two histochemically different fiber types (dorsal and ventral groups) revealed large hyperpolarizations in the ventral fibers and decreased duration and amplitude of excitatory potentials in the dorsal fibers. These results suggest that there are a variety of ways in which tension can be evoked, maintained, and controlled in these muscles.

Animals↗

PubMed1976

Experimental panencephalitis induced in suckling mice, by parainfluenza type 1 (6/94) virus, II. Virologic studies.

6/94 virus, a parainfluenza type 1 isolate from multiple sclerosis brain tissue, produced a chronic panencephalitis when inoculated intracerebrally into suckling ICR mice. Immunofluorescent staining revealed 6/94 viral antigen in ependyma, meninges, choroid plexus, and perivascular parenchymal sites from day 3 to 128 days after infection. Hemadsorption-neutralizing antibody was first detected between 20-25 days after infection and remained at high titers for 7 months. Using embryonated chicken eggs, virus was recovered from mouse brains for only 8 days, but could be recovered from brains grown in vitro as explants for 37 days after infection. In cell lines established from explanted brain tissue, immunofluorescence was the most sensitive indicator of virus presence, although infectious virus was not produced. Fusion of these mouse brain cells with human (W138) indicator cells was the most effective means of rescuing 6/94 virus.

Animals↗