Biomedical subjects

M Chynoranský

Publications and source records attributed to M Chynoranský.

At least 19 recordsLinked to original sources

PubMed1997

[Rhabdomyosarcoma of the orbit].

The authors evaluated 9 years' experience with the diagnosis and treatment of embryonic rhabdomyosarcoma of the orbit in children. They evaluated in detail a group of 5 children treated and followed up for 1-9 years. Due to comprehensive surgical, radiation and chemotherapeutic treatment all patients survive and in 80% the visual function is preserved. For differential diagnostic problems, with regard to the variable manifestation of rhabdomyosarcoma which may imitate orbitocellulitis, chalaseon, epibulbar lipodermoid or papilloma, the authors emphasize the importance of rapid primary diagnosis by NMR and biopsy. In the treatment they appreciate greatly a combination of radiotherapy and chemotherapy which is a modern trend and can eradicate the tumour without radical surgery.

Child↗

PubMed1997

[Evaluation of the retrobulbar space in Graves' orbitopathy using color Doppler ultrasonography].

UNLABELLED: Authors evaluated B-scan findings, blood flow velocity of orbital vessels. At vena Orbitalis Superior (VOS) they evaluated width of color echo and course of blood flow only too. CONCLUSION: 1. GO significantly influences blood flow only in VOS-alteration of blood flow velocities = 7-25 cm/s, nonconstant changing of course blood flowing and dilatation of color echo of the VOS, 2. Thickening of the extraocular muscles significantly influences dilatation of color echo of the VOS, what is a sign of worsening of venous drainage in orbital apex. 3. Swollen connective tissue is displayed as extensive hyperintensive, homogeneous echo retrobulbar, connecting always with subjective pressure, pain beyond the eye.

Blood Flow Velocity↗

PubMed1997

[Diagnosis of carotid-cavernous fistula using color Doppler ultrasonography].

The authors evaluated orbital haemodynamics by Colour Doppler flow Information (CDFI), in 4 cases of carotid-venous fistulas (CCF). Significant changes were demonstrated only in the superior orbital vein (SOV) = 1. Changing of course blood flowing-biodirect (as an alternating orthograde and retrograde) blood flow, or constant retrograde blood flow in SOV, independent from Valsalva manoeuver. 2. Pulsating SOV, in spectral analyse as a retrograde blood flow is synchroned with cordial rhythm on electrocardiography record. 3. Dilatation of color echo of the VOS is a nonconstant sign of CCF.

Aged↗

PubMed1996

[Diseases of the orbit in children].

The authors analyze their 8-years experience and therapeutic results achieved in 78 hospitalized children with different pathological conditions of the orbit. The spectrum of diseases comprised in 38% congenital anomalies, 22% tumors, 22% traumatic accidents, 13% was for orbital manifestations of systemic disease and in 5% inflammatory processes participated. The majority of patients were operated and the remainder was treated by conservative methods. The therapeutic results and other important aspects of orbital diseases are discussed.

Child↗

PubMed1996

[Therapeutic effectiveness of local administration of corticosteroids in the treatment of orbital capillary hemangioma].

The author evaluated three years experience with the treatment of capillary haemangioma of the orbit and eyelids in nine infants. They used several therapeutic methods. However, they injected in all patients depot corticosteroids-Triamcinolone-into the tumour. Indication for treatment was a marked cosmetic defect, imminent amblyopia and progression of the haemangioma. The results of steroid treatment are very good from the cosmetic and functional aspect. Indications for treatment, results and differential diagnostic problems are discussed.

Eyelid Neoplasms↗

PubMed1994

[Exophthalmus caused by diseases of the lacrimal glands].

In the submitted paper the authors analyze data from a selected patient group with diseases of the orbit and evaluate the ratio of diseases of the lacrimal gland at the First Ophthalmological Clinic Faculty Hospital, Medical Faculty Comenius University in Bratislava between 1980 and 1992. During the mentioned period 25 patients with orbital disease were hospitalized or put on records and dispensarized. Tumours of the lacrimal glands were present 16 times.

Exophthalmos↗

PubMed1994

[Exenteration of the orbit].

The authors evaluate the number and results of exenterations of the orbit on account of malignant neoplasms originating in intraocular structures and penetrating into the orbit or malignant processes originating in structures of the orbital contents and tissues surrounding the orbit. These operations were made in a group of 156 patients with orbital disease hospitalized at the First Ophthalmological Clinic, Faculty Hospital and Medical Faculty, Comenius University, Bratislava in 1980-1992. During the mentioned 13-year period exenteration of the orbit was indicated in 22 patients, i.e. 14.1% from the total number of 156 hospitalized patients with orbital disease.

Aged↗

PubMed1994

[Diseases of the orbit].

In the submitted paper the authors analyze data from a group of patients with diseases of the orbit treated at the First Ophthalmological Clinic, Faculty Hospital, Medical Faculty Comenius University Bratislava between the beginning of 1980 and the end of 1992. During the mentioned period 156 patients with orbital diseases were hospitalized or put on record. The 13-year group of patients is evaluated from the aspect of causes of exophthalmos, age distribution, lateralization of the disease and different diseases by sex. Special attention is paid to a sub-group of 70 patients with tumours of the orbit.

Adolescent↗

PubMed1990

[The effect of diazepam on the electroretinogram].

The effect of some drugs on electric potentials of the retina has been described in the literature. Data on the effect of drugs of the group of benzodiazepines on electric potentials of the retina in man have not come to our attention. In the present study diazepam was found to affect substantially the studied parameters of the electroretinogram. An inhibitory effect of diazepam on the electric response of the retina was established. The period of latency and that of culmination of the electroretinogram were found to be most intensively affect.

Adult↗

PubMed1990

[Causes of blindness and low vision in children in Slovakia].

The authors analyze the causes of blindness in children, of Low Vision and hospital admission among pupils of the school for blind children in Levoca, a primary school for children with visual debility in Bratislava and in hospitalized children at the Ophthalmological Clinic, Faculty Hospital Bratislava. The main causes of severe visual disorders in children are in as many as 90% inborn or hereditary diseases. The latter account for 48% of the reasons for hospital admission. The authors draw attention to the increasing incidence of numerous prenatally conditioned diseases as the dominating cause of serious visual disorders in children. In this context they submit recommendations for the improvement of comprehensive care of children with defective eyesight.

Blindness↗

PubMed1990

[Coat's syndrome in our data].

The authors submit the results of 10 years' observation and treatment of 10 children with Coats syndrome. They emphasize early diagnosis and importance of the differential diagnosis with retinoblastoma in some problematic cases. They consider photocoagulation very effective, which in eight treated children not only arrested the progression of the disease but caused also absorption of retinal exudates.

Adolescent↗

PubMed1990

[Bilateral congenital anophthalmos].

The author describes the rare occurrence of congenital bilateral anophthalmos in a child with unilateral microphthalmus in the mother. The grandmother worked for a long time as an X-ray laboratory assistant without adequate protection against ionizing radiation. The cause of the development of pathological conditions in our proband and his mother is most probably a dominant "de novo" mutation in the germinal cells of the grandmother exposed to radiation. The transmission is according to our findings autosomal dominating with a variable expressivity.

Anophthalmos↗

PubMed1990

[Electrical activity of the retina].

The site of origin, propagation, and recording of eye potentials are described. Action potentials of the eye and the mechanism of their origin are briefly characterized. The origin of individual potentials, which produce the individual waves of the action potential in the clinical record, is presented in the literary survey. The characteristics of the human electroretinogram (ERG) are given, factors affecting individual parts of the curve are described and the role of individual layers of the retina in their development is determined. Some characteristic changes in the ERG curve observed at damage of the rods and cones are presented.

Action Potentials↗

PubMed1990

[Factors affecting the electroretinogram].

The author describes the factors which quantitatively modify some components of the electroretinogram (ERG) and have thus to be accounted for on evaluating the results of electrophysiologic parameters studied. Appreciation of the effect of individual factors on the ERG objectifies the assessment of retinal function.

Age Factors↗

PubMed1990

[Ectopic lens in childhood].

The authors analyze a group of 34 patients with ectopy of the lens detected in childhood and followed up for 12 years. The ectopy of the lens was not restricted to the eye but was part of numerous syndromes. The authors emphasize aetiological diagnosis, interdisciplinary collaboration and evaluation whether surgical extraction of the lens is indicated. Indication for operation is incorrigible reduction of the visual acuity below 0.3 and the imminence of complete dislocation of the lens. The long-term results of 12 operated patients are despite some complications very satisfactory from the functional aspect.

Child↗

PubMed1989

[Terrien's corneal dystrophy].

In clinical and histomorphological case-history of a 27-year-old man the authors describe a rare corneal finding where Terrien's corneal dystrophy was confirmed. Correct evaluation of the clinical stage of the disease is considered important for the indication of microsurgical treatment. Light and electron microscopy made it possible to diagnose the dystrophic form of the disease and the clinical course confirmed the indication of surgical treatment.

Adult↗

PubMed1989

[The Hallermann-Streiff syndrome in 2 generations].

The authors discuss a rare case, unique in our literature, of the familial incidence of Hallermann-Streiff's syndrome and the treatment of some of its complications. Special emphasis is laid on genetic analysis which provides evidence of autosomal dominant heredity with a variable expressivity of the pathological gene, and which must be applied in genetic consultations.

Adult↗

PubMed1989

[Familial exudative Criswick-Schepens vitreoretinopathy].

The authors describe their own observation of a very rare form of vitreoretinal degeneration in a young man classified as familial exudative Criswick-Schepens vitreoretinopathy. The disease was detected in the second clinical stage on the right eye and in the third clinical stage on the left eye. The transmission of the disease is autosomal dominant with incomplete penetration. In the paper special emphasis is laid on differential diagnostic problems and the possibility of treatment of this disease.

Adult↗